Evidence map›Paper›PMID 34682277›Full record

ReviewJournal of fungi (Basel, Switzerland)2021

Update on Dihydropteroate Synthase (DHPS) Mutations in

Carmen de la Horra, Vicente Friaza, Rubén Morilla, Juan Delgado, Francisco J Medrano, Robert F Miller, Yaxsier de Armas, Enrique J Calderón

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06431958 (Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis Jirovecii), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06431958 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis Jirovecii

TypeobservationalSponsorUniversity Hospital, BrestRan2024 to 2026Enrolled300ConditionsPneumocystis Pneumonia
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. CRISPR-Cas12 Application for the Detection ofInternational journal of molecular sciences · 2025
    Article
  5. Molecular Study ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  6. Analysis of Mutations inInfection and drug resistance · 2024
    Article
  7. Molecular Analysis of Dihydropteroate Synthase Gene Mutations inInternational journal of molecular sciences · 2023
    Article
  8. Trends in the Epidemiology ofJournal of fungi (Basel, Switzerland) · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Multilocus Genotyping ofJournal of fungi (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Carmen de la HorraInstituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, 41013 Seville, Spain.
Vicente FriazaInstituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, 41013 Seville, Spain.
Rubén MorillaInstituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, 41013 Seville, Spain.
Juan DelgadoInstituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0002-5947-6287
Francisco J MedranoInstituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, 41013 Seville, Spain.ORCID 0000-0001-5863-344X
Robert F MillerInstitute for Global Health, University College London, London WC1E 6JB, UK.ORCID 0000-0003-2067-4291
Yaxsier de ArmasDepartment of Clinical Microbiology Diagnostic, Hospital Center of Institute of Tropical Medicine "Pedro Kourí", Havana 11400, Cuba.
Enrique J CalderónInstituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/Consejo Superior de Investigaciones Científicas/Universidad de Sevilla, 41013 Seville, Spain.
Instituto de Biomedicina de Sevilla · ESInstituto de Medicina Tropical “Pedro Kourí” · CUUniversity of London · GB

Funding

Instituto de Salud Carlos III FIS- PI19/01845
6 · The paper itself

Abstract

A

Indexed as

dihydropteroate synthasegene mutationspneumocystis

Identifiers

PMID34682277
PMCPMC8540849
OpenAlexW3206784178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.