Evidence map›Paper›PMID 34682125›Full record

ReviewChildren (Basel, Switzerland)2021

Management of Infectious Lymphadenitis in Children.

Francesco Pecora, Luciana Abate, Sara Scavone, Irene Petrucci, Federico Costa, Caterina Caminiti, Alberto Argentiero, Susanna Esposito

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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  6. Article
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  11. Maxillofacial infections in lithuanian hospitalised children and adolescents: a 17-years retrospective study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2023
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Francesco PecoraPaediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126 Parma, Italy.
Luciana AbatePaediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126 Parma, Italy.
Sara ScavonePaediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126 Parma, Italy.
Irene PetrucciPaediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126 Parma, Italy.
Federico CostaPaediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126 Parma, Italy.
Caterina CaminitiResearch an Innovation Unit, University Hospital of Parma, via Gramsci 14, 43126 Parma, Italy.ORCID 0000-0002-3196-2435
Alberto ArgentieroPaediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126 Parma, Italy.
Susanna EspositoPaediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126 Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphadenopathy is an irregularity in the size and texture of the lymph nodes, which is quite common in childhood. When the enlargement of lymph nodes is caused by inflammatory and infectious processes, it is called lymphadenitis. The main objective of this manuscript is to summarize the common infectious etiologies and presentations of lymphadenitis in children providing a management guide for clinical practice. PubMed was used to search for all of the studies published up to April 2021 using keywords such as "lymphadenitis" and "children". Literature analysis showed that the differential diagnosis for lymphadenitis in pediatrics is broad. Although lymph node enlargement in children is usually benign and self-limited, it is important to exclude malignant etiology. In most cases, history and physical examination allow to identify the correct diagnosis and start a proper treatment with a prompt resolution of the lymphadenopathy. However, particularly in the case of persistent lymphadenitis, determining the cause of lymph node enlargement may be difficult, and the exact etiology may not be identified despite extensive investigations. Further studies should develop and validate an algorithm to assist pediatricians in the diagnosis and timely treatment of lymphadenitis, suggesting situations in which a watchful waiting may be considered a safe approach, those in which empiric antibiotic therapy should be administered, and those requiring a timely diagnostic work-up.

Indexed as

Bartonella henselaechildrenlymphadenitismycobacterium avium complex

Identifiers

PMID34682125
PMCPMC8535130
OpenAlexW3201995870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.