ArticleChildren (Basel, Switzerland)2021
Iatrogenic Blood Loss in Very Low Birth Weight Infants and Transfusion of Packed Red Blood Cells in a Tertiary Care Neonatal Intensive Care Unit.
Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Blood loss due to diagnostic testing in extremely preterm infants in 22 European countries: a prospective observational study.EClinicalMedicine · 2026Article
- Management of neonatal massive hemorrhage: A narrative review.Transfusion · 2026Review
- Umbilical cord blood collection at birth reduces early iatrogenic blood loss in preterm infants with birth weights <1,500 g.Frontiers in pediatrics · 2026Article
- Risk factors associated with anemia of prematurity requiring red blood cell transfusion in very low birth weight infants: a retrospective study.BMC pediatrics · 2024Article
- Development and validation of a novel risk classification tool for predicting long length of stay in NICU blood transfusion infants.Scientific reports · 2024Article
- The Early Hematological Profile and Its Variations: A Useful Tool in the Prediction of Intraventricular Hemorrhage in Extremely Preterm Infants.Medicina (Kaunas, Lithuania) · 2024Article
- Current status and future directions of application of urine proteomics in neonatology.Frontiers in pediatrics · 2024Review
- Changes to Blood-Sampling Protocol to Reduce the Sampling Amount in Neonatal Intensive Care Units: A Quality Improvement Project.Journal of clinical medicine · 2023Article
- Age and sex trend differences in hemoglobin levels in China: a cross-sectional study.BMC endocrine disorders · 2023Article
- Stabilization and Resuscitation of Newborns.Children (Basel, Switzerland) · 2022Article
- Thresholds for blood transfusion in extremely preterm infants: A review of the latest evidence from two large clinical trials.Frontiers in pediatrics · 2022Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An adequate blood volume is important for neonatal adaptation. The study objective was to quantify the cumulative iatrogenic blood loss in very low birth weight (VLBW) infants by blood sampling and the necessity of packed red cell transfusions from birth to discharge from the hospital. In total, 132 consecutive VLBW infants were treated in 2019 and 2020 with a median birth weight of 1180 g (range 370-1495 g) and a median length of stay of 54 days (range 0-154 days) were included. During the initial four weeks of life, the median absolute amount of blood sampling was 16.5 mL (IQR 12.3-21.1 mL), sampling volume was different with 14.0 mL (IQR 12.1-16.2 mL) for non-transfused infants and 21.6 mL (IQR 17.5-29.4 mL) for transfused infants. During the entire length of stay, 31.8% of the patients had at least one transfusion. In a generalized logistic regression model, the cumulative amount of blood sampling (
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