Evidence map›Paper›PMID 34682103›Full record

ArticleChildren (Basel, Switzerland)2021

Fifteen-Years Follow-Up in a Cohort of Children with Functional Gastrointestinal Disorders: Prevalence and Risk Factors to Develop Neuropsychiatric Disorders and Other Comorbidities.

Chiara Zanchi, Stefano Pintaldi, Grazia Di Leo, Luca Ronfani, Giulia Zamagni, Marialuisa Viel, Egidio Barbi, Giorgio Cozzi

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chiara ZanchiDepartment of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Via dell'Istria 65, 34137 Trieste, Italy.ORCID 0000-0001-8513-1963
Stefano PintaldiDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Grazia Di LeoDepartment of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Via dell'Istria 65, 34137 Trieste, Italy.
Luca RonfaniEpidemiology and Biostatistics Unit, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0001-5710-3914
Giulia ZamagniEpidemiology and Biostatistics Unit, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-4949-3219
Marialuisa VielDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.
Egidio BarbiDepartment of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Via dell'Istria 65, 34137 Trieste, Italy.ORCID 0000-0002-6343-846X
Giorgio CozziDepartment of Pediatrics, Institute for Maternal and Child Health "IRCCS Burlo Garofolo", Via dell'Istria 65, 34137 Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional gastrointestinal disorders (FGIDs) are chronic and recurrent disorders, which affect up to 23% of children and adolescents and represent 50% of gastroenterological accesses. The association between FGIDs diagnosed at paediatric age and the onset of migraine or headache and neuropsychiatric diseases in adolescence and adulthood is widely reported in the literature. However, there is still limited knowledge about the long-term prognosis and risk factors for neuropsychiatric pathologies and other comorbidities.

aimThe aim is to assess the prevalence and persistence of FGIDs as well as the occurrence of migraine or headache and neuropsychiatric disorders in a cohort of patients diagnosed with FGIDs 15 years ago compared with a control group of peers. MATERIALS AND

methodsWe enrolled a group of patients diagnosed with FGIDs at paediatric age, at least 10 years ago (FGIDs group,

results45.6% (36 out of 79) of patients previously diagnosed with FGIDs still suffer from FGIDs versus 12% (24 out of 201) of healthy controls (

conclusionThe outcome at 15 years of FGIDs was characterized by a high prevalence of persisting functional symptoms along with a significant incidence of headaches and migraines. Abbreviation: FGIDs: Functional gastrointestinal disorders; IBS: Inflammatory Bowel Syndrome.

Indexed as

functional gastrointestinal disordersheadachemigraine and chronic intestinal diseases

Identifiers

PMID34682103
PMCPMC8534479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.