Evidence map›Paper›PMID 34681921›Full record

ReviewInternational journal of molecular sciences2021

Multi-Omics Analysis of Gut Microbiota in Inflammatory Bowel Diseases: What Benefits for Diagnostic, Prognostic and Therapeutic Tools?

Vickie Lacroix, Alexis Cassard, Emmanuel Mas, Frederick Barreau

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  7. Review
  8. Review
  9. The Microbiome in Inflammatory Bowel Disease.Journal of clinical medicine · 2024
    Review
  10. Article
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vickie LacroixGastroenterology, Hepatology, Nutrition, Diabetology and Hereditary Metabolic Diseases Unit, Children's Hospital, CHU de Toulouse, 31300 Toulouse, France.
Alexis CassardDepartment of Nephrology and Organ Transplantation, Rangueil Hospital, CHU de Toulouse, 31300 Toulouse, France.
Emmanuel MasGastroenterology, Hepatology, Nutrition, Diabetology and Hereditary Metabolic Diseases Unit, Children's Hospital, CHU de Toulouse, 31300 Toulouse, France.ORCID 0000-0001-5425-7352
Frederick BarreauIRSD, University of Toulouse, INSERM, INRAE, ENVT, UPS, 31024 Toulouse, France.ORCID 0000-0002-7150-9619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel diseases (IBDs), which include Crohn's disease and ulcerative colitis, are multifactorial diseases that involve in particular a modification of the gut microbiota, known as dysbiosis. The initial sets of metataxonomic and metagenomic data first made it possible to approximate the microbiota profile in IBD. In addition, today the new 'omics' techniques have enabled us to draw up a functional and integrative map of the microbiota. The key concern in IBD is to develop biomarkers that allow us to assess the activity of the disease and predict the complications and progression, while also guiding the therapeutic care so as to develop personalized medicine. In this review, we present all of the latest discoveries on the microbiota provided by "omics" and we outline the benefits of these techniques in developing new diagnostic, prognostic and therapeutic tools.

Indexed as

BacteriaDisease ProgressionGastrointestinal MicrobiomeHumansInflammatory Bowel DiseasesMetagenomicsPhylogenyPrecision MedicineCrohn’s diseaseinflammatory bowel diseasemicrobiotaomicsulcerative colitis

Identifiers

PMID34681921
PMCPMC8537481

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.