Evidence map›Paper›PMID 34681909›Full record

ArticleInternational journal of molecular sciences2021

Macrophage-Dependent Interleukin-6-Production and Inhibition of

Md Kamrul Hasan Chowdhury, Laura Martinez-Mateu, Jenny Do, Kelly A Aromolaran, Javier Saiz, Ademuyiwa S Aromolaran

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Obesity Arrhythmias: Role of IL-6 Trans-Signaling.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Observational
  15. Review
  16. New Insights into Cardiac Ion Channel Regulation 2.0.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Md Kamrul Hasan ChowdhuryNora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT 84112, USA.
Laura Martinez-MateuSignal Theory, Communications, Telematic Systems and Computation Department, Telecommunications Engineers School, King Juan Carlos University, 28942 Madrid, Spain.ORCID 0000-0003-0291-7683
Jenny DoMasonic Medical Research Institute, Utica, NY 13501, USA.
Kelly A AromolaranNora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT 84112, USA.
Javier SaizCentro de Investigación e Innovación en Bioingeniería, Universitat Politècnica de València, 46022 Valencia, Spain.
Ademuyiwa S AromolaranNora Eccles Harrison Cardiovascular Research and Training Institute (CVRTI), University of Utah, Salt Lake City, UT 84112, USA.
University of Utah · USMasonic Medical Research Laboratory · USUniversidad Rey Juan Carlos · ESUniversitat Politècnica de València · ES

Funding

Mechanisms of Lipotoxic ArrhythmiasR01HL147044 · NHLBI · UNIVERSITY OF UTAH · PI AROMOLARAN, ADEMUYIWA · 2019 to 2022
$1.5M
Channelopathies of InflammationR01HL177965 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Ademuyiwa Aromolaran · 2025 to 2026
$1.2M
NHLBI NIH HHS R01 HL147044NHLBI NIH HHS R01 HL177965NIH HHS R01 HL147044
6 · The paper itself

Abstract

In the heart, the delayed rectifier K current,

Indexed as

Action PotentialsAnimalsArrhythmias, CardiacCardiotoxicityFemaleGuinea PigsInterleukin-6Ion Channel GatingLipid MetabolismLong QT SyndromeMacrophagesMyocytes, CardiacPotassium ChannelsInterleukin-6Potassium Channelscytokinesguinea piginflammationinterleukin-6lipotoxicityQT prolongationventricular myocytes

Identifiers

PMID34681909
PMCPMC8537919
OpenAlexW3205987292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.