Evidence map›Paper›PMID 34681900›Full record

ArticleInternational journal of molecular sciences2021

Long Intergenic Noncoding RNA

Toshihiko Takeiwa, Yuichi Mitobe, Kazuhiro Ikeda, Kosei Hasegawa, Kuniko Horie, Satoshi Inoue

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Immunotherapeutic Approaches in Ovarian Cancer.Current issues in molecular biology · 2023
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Toshihiko TakeiwaDivision of Systems Medicine & Gene Therapy, Saitama Medical University, Hidaka, Saitama 350-1241, Japan.
Yuichi MitobeDivision of Systems Medicine & Gene Therapy, Saitama Medical University, Hidaka, Saitama 350-1241, Japan.
Kazuhiro IkedaDivision of Systems Medicine & Gene Therapy, Saitama Medical University, Hidaka, Saitama 350-1241, Japan.
Kosei HasegawaDepartment of Gynecologic Oncology, Saitama Medical University International Medical Center, Hidaka, Saitama 350-1298, Japan.ORCID 0000-0002-1903-7001
Kuniko HorieDivision of Systems Medicine & Gene Therapy, Saitama Medical University, Hidaka, Saitama 350-1241, Japan.
Satoshi InoueDivision of Systems Medicine & Gene Therapy, Saitama Medical University, Hidaka, Saitama 350-1241, Japan.ORCID 0000-0003-1247-3844
Saitama Medical University · JPTokyo Metropolitan Institute of Gerontology · JP

Funding

Japan Society for the Promotion of Science 20H03734Japan Society for the Promotion of Science 20K08916Japan Society for the Promotion of Science 20K21636Japan Society for the Promotion of Science 20K21667Japan Society for the Promotion of Science 21K16798Promotion and Mutual Aid Corporation for Private Schools of Japan Science Research Promotion FundTakeda Science Foundation GrantVehicle Racing Commemorative Foundation Grant
6 · The paper itself

Abstract

Patients with advanced ovarian cancer usually exhibit high mortality rates, thus more efficient therapeutic strategies are expected to be developed. Recent transcriptomic studies revealed that long intergenic noncoding RNAs (lincRNAs) can be a new class of molecular targets for cancer management, because lincRNAs likely exert tissue-specific activities compared with protein-coding genes or other noncoding RNAs. We here show that an unannotated lincRNA originated from chromosome 10q21 and designated as

Indexed as

Gene Expression Regulation, NeoplasticAnimalsApoptosisBiomarkers, TumorCell ProliferationFemaleHumansMiceMice, Inbred BALB CMice, NudeOvarian NeoplasmsPrognosisRNA, Long NoncodingSequence Analysis, RNATumor Cells, CulturedXenograft Model Antitumor AssaysBiomarkers, TumorRNA, Long Noncodinglong intergenic noncoding RNA (lincRNA)ovarian cancerRNA sequencingsmall interfering RNA (siRNA)xenograft

Identifiers

PMID34681900
PMCPMC8541687
OpenAlexW3205008499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.