Evidence map›Paper›PMID 34681872›Full record

ArticleInternational journal of molecular sciences2021

Tension Stimulation of Tenocytes in Aligned Hyaluronic Acid/Platelet-Rich Plasma-Polycaprolactone Core-Sheath Nanofiber Membrane Scaffold for Tendon Tissue Engineering.

Chih-Hao Chen, Dai-Ling Li, Andy Deng-Chi Chuang, Banendu Sunder Dash, Jyh-Ping Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 50 citations in OpenAlex.

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  19. Review
  20. Advanced Robotics to Address the Translational Gap in Tendon Engineering.Cyborg and bionic systems (Washington, D.C.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Chih-Hao ChenDepartment of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Keelung, Keelung 20401, Taiwan.ORCID 0000-0001-7213-2596
Dai-Ling LiDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan 33302, Taiwan.
Andy Deng-Chi ChuangDepartment of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Keelung, Keelung 20401, Taiwan.ORCID 0000-0002-0035-6723
Banendu Sunder DashDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-7546-3902
Jyh-Ping ChenDepartment of Plastic and Reconstructive Surgery and Craniofacial Research Center, Chang Gung Memorial Hospital at Linkou, Collage of Medicine, Chang Gung University, Taoyuan 33305, Taiwan.ORCID 0000-0001-6527-4801
Chang Gung University · TWKeelung Chang Gung Memorial Hospital · TWMing Chi University of Technology · TW

Funding

Chang Gung Memorial Hospital CMRPD2J0113Ministry of Science and Technology MOST109-2314-B-182-013-MY3
6 · The paper itself

Abstract

To recreate the in vivo niche for tendon tissue engineering in vitro, the characteristics of tendon tissue underlines the use of biochemical and biophysical cues during tenocyte culture. Herein, we prepare core-sheath nanofibers with polycaprolactone (PCL) sheath for mechanical support and hyaluronic acid (HA)/platelet-rich plasma (PRP) core for growth factor delivery. Three types of core-sheath nanofiber membrane scaffolds (CSNMS), consisting of random HA-PCL nanofibers (Random), random HA/PRP-PCL nanofibers (Random+) or aligned HA/PRP-PCL (Align

Indexed as

TendonsTenocytesAnimalsCell Culture TechniquesCell ProliferationCollagenElastic ModulusHyaluronic AcidMaterials TestingMicroscopy, Electron, ScanningNanofibersPlatelet-Rich PlasmaPolyestersRabbitsThermogravimetryTissue EngineeringCollagenHyaluronic AcidpolycaprolactonePolyestersaligned nanofibersbioreactorelectrospinninghyaluronic acidplatelet-rich plasmatendon tissue engineering

Identifiers

PMID34681872
PMCPMC8537129
OpenAlexW3206773356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.