Evidence map›Paper›PMID 34681836›Full record

ArticleInternational journal of molecular sciences2021

Inhibition of Spinal TRPV1 Reduces NMDA Receptor 2B Phosphorylation and Produces Anti-Nociceptive Effects in Mice with Inflammatory Pain.

Suk-Yun Kang, Su Yeon Seo, Se Kyun Bang, Seong Jin Cho, Kwang-Ho Choi, Yeonhee Ryu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. TRP Channels in Excitotoxicity.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025
    Review
  8. Utilization of Cannabidiol in Post-Organ-Transplant Care.International journal of molecular sciences · 2025
    Review
  9. Review
  10. Neuroplasticity in the transition from acute to chronic pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
  11. TRPV1: The key bridge in neuroimmune interactions.Journal of intensive medicine · 2024
    Review
  12. Article
  13. Article
  14. Antinociceptive Effect ofLife (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Article
  17. Neuro-Plastic Mechanisms of Pain and Addiction.International journal of molecular sciences · 2022
    Article
  18. The Effect of Ginger and Its Sub-Components on Pain.Plants (Basel, Switzerland) · 2022
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Suk-Yun KangKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.ORCID 0000-0001-6812-9503
Su Yeon SeoKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Se Kyun BangKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Seong Jin ChoKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Kwang-Ho ChoiKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Yeonhee RyuKM Science Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Korea Institute of Oriental Medicine · KR

Funding

Korea Institute of Oriental Medicine KSN2021210
6 · The paper itself

Abstract

Transient receptor potential vanilloid 1 (TRPV1) has been implicated in peripheral inflammation and is a mediator of the inflammatory response to various noxious stimuli. However, the interaction between TRPV1 and

Indexed as

InflammationAnalgesicsAnimalsCapsaicinCarrageenanDisease Models, AnimalGlutamic AcidHyperalgesiaMaleMiceMice, Inbred ICRPainPhosphorylationReceptors, N-Methyl-D-AspartateSpinal CordTRPV Cation ChannelsAnalgesicsCapsaicincapsazepineCarrageenanGlutamic AcidNR2B NMDA receptorReceptors, N-Methyl-D-AspartateTRPV1 protein, mouseTRPV Cation Channelscapsazepineglutamateinflammatory painN-methyl-D-aspartate (NMDA)transient receptor potential vanilloid 1 (TRPV1)

Identifiers

PMID34681836
PMCPMC8539417
OpenAlexW3206628795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.