Evidence map›Paper›PMID 34681828›Full record

ArticleInternational journal of molecular sciences2021

Long Non-Coding RNA

Adam M Lee, Asmaa Ferdjallah, Elise Moore, Daniel C Kim, Aritro Nath, Emily Greengard, R Stephanie Huang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Potential Links Between ANRIL and MiRNAs in Various Cancers.Combinatorial chemistry & high throughput screening · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Emerging roles of long non-coding RNAs in osteosarcoma.Frontiers in molecular biosciences · 2024
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Non-coding antisense transcripts: fine regulation of gene expression in cancer.Computational and structural biotechnology journal · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Adam M LeeDepartment of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.
Asmaa FerdjallahDepartment of Pediatrics, Hematology & Oncology, University of Minnesota, Minneapolis, MN 55455, USA.
Elise MooreDepartment of Natural Sciences, Zanvyl Krieger School of Arts and Sciences, The Johns Hopkins University, Baltimore, MD 21218, USA.
Daniel C KimDepartment of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0003-0919-3569
Aritro NathDepartment of Medical Oncology and Therapeutics, City of Hope Comprehensive Cancer Center, Monrovia, CA 91007, USA.
Emily GreengardDepartment of Pediatrics, Hematology & Oncology, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-2963-5638
R Stephanie HuangDepartment of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.ORCID 0000-0002-9862-0368
University of Minnesota · USCity of Hope · USJohns Hopkins University · US

Funding

Genetic mechanisms underlying sexual dimorphism in cancer and response to therapyR01CA229618 · NCI · UNIVERSITY OF COLORADO DENVER · PI HUANG, RONG STEPHANIE, STRANGER, BARBARA E · 2019 to 2024
$2.9M
Drug repurposing in breast cancerR01CA204856 · NCI · UNIVERSITY OF MINNESOTA · PI HUANG, RONG STEPHANIE · 2018 to 2022
$2.2M
National Cancer Institute R01CA204856National Cancer Institute R01CA229618
6 · The paper itself

Abstract

Osteosarcoma has a poor prognosis due to chemo-resistance and/or metastases. Increasing evidence shows that long non-coding RNAs (lncRNAs) can play an important role in drug sensitivity and cancer metastasis. Using osteosarcoma cell lines, we identified a positive correlation between the expression of a lncRNA and

Indexed as

Antineoplastic AgentsBiomarkers, TumorBone NeoplasmsCell Line, TumorCisplatinDoxorubicinDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansOsteosarcomaPrognosisRNA, Long NoncodingAntineoplastic AgentsBiomarkers, TumorCDKN2B antisense RNA, humanCisplatinDoxorubicinRNA, Long NoncodingANRILCDKN2B-AS1chemosensitivitycisplatindoxorubicinlong non-coding RNAosteosarcoma

Identifiers

PMID34681828
PMCPMC8538287
OpenAlexW3206055509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.