Evidence map›Paper›PMID 34681806›Full record

ArticleInternational journal of molecular sciences2021

Synergistic Action of Antimicrobial Lung Proteins against

Víctor Fraile-Ágreda, Olga Cañadas, Timothy E Weaver, Cristina Casals

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Differential Scanning Calorimetry of Protein-Lipid Interactions.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Membrane-Peptide Interactions: From Basics to Current Applications 2.0.International journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Víctor Fraile-ÁgredaDepartment of Biochemistry and Molecular Biology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1561-1328
Olga CañadasDepartment of Biochemistry and Molecular Biology, Complutense University of Madrid, 28040 Madrid, Spain.
Timothy E WeaverDivision of Pulmonary Biology, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.
Cristina CasalsDepartment of Biochemistry and Molecular Biology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-2696-0918
Universidad Complutense de Madrid · ESCincinnati Children's Hospital Medical Center · US

Funding

National Institutes of Health R01 HL134186 and R01 HL103923Spanish Ministry of Science, Innovation and Universities SAF2015-65307-R and RTI2018-094355-BI00
6 · The paper itself

Abstract

As key components of innate immunity, lung antimicrobial proteins play a critical role in warding off invading respiratory pathogens. Lung surfactant protein A (SP-A) exerts synergistic antimicrobial activity with the

Indexed as

Anti-Bacterial AgentsBronchoalveolar Lavage FluidDrug SynergismHumansImmunity, InnateKlebsiella InfectionsKlebsiella pneumoniaeLungMicrobial Sensitivity TestsPulmonary Surfactant-Associated Protein APulmonary SurfactantsRespiratory Tract InfectionsAnti-Bacterial AgentsPulmonary Surfactant-Associated Protein APulmonary Surfactantsantimicrobial peptidesdifferential scanning calorimetrylipid vesiclesmembrane probesmultidrug-resistant bacteriapeptide–membrane interactionspulmonary surfactantSP-ASP-BNsynergy

Identifiers

PMID34681806
PMCPMC8538444
OpenAlexW3207080205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.