Evidence map›Paper›PMID 34681769›Full record

ArticleInternational journal of molecular sciences2021

Rutaecarpine, an Alkaloid from

Chun-Jen Huang, Wei-Chieh Huang, Wei-Ting Lin, Lan-Hsin Shu, Joen-Rong Sheu, Oanh-Thi Tran, Chih-Wei Hsia, Thanasekaran Jayakumar, Periyakali Saravana Bhavan, Cheng-Ying Hsieh and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  9. Molecular Research on Platelet Activity in Health and Disease 3.0.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Chun-Jen HuangDepartment of Anesthesiology and Integrative Research Center for Critical Care, Wan Fang Hospital, Taipei Medical University, Taipei 110, Taiwan.
Wei-Chieh HuangGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Wei-Ting LinGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Lan-Hsin ShuDepartment of Nutrition, Chung Shan Medical University, Taichung 402, Taiwan.
Joen-Rong SheuGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-8265-3678
Oanh-Thi TranInternational Ph.D. Program for Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chih-Wei HsiaGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-4508-6181
Thanasekaran JayakumarGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Periyakali Saravana BhavanDepartment of Zoology, Bharathiar University, Coimbatore 641046, Tamil Nadu, India.ORCID 0000-0003-2056-4607
Cheng-Ying HsiehDepartment of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chao-Chien ChangDepartment of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Taipei Medical University · TWBharathiar University · INFu Jen Catholic University · TWWan Fang Hospital · TW

Funding

Cathay General Hospital CGH-MR-A11005Cathay General Hospital-Taipei Medical University 108CGH-TMU-07Ministry of Science and Technology, Taiwan MOST 107-2320-B-038-035-MY2Ministry of Science and Technology, Taiwan MOST 108-2320-B-038-031-MY3Taipei Medical University DP2-107-21121-N-02Taipei Medical University-Wan Fang Hospital 107TMU-WFH-06
6 · The paper itself

Abstract

The role of activated platelets in acute and chronic cardiovascular diseases (CVDs) is well established. Therefore, antiplatelet drugs significantly reduce the risk of severe CVDs.

Indexed as

AlkaloidsAnimalsCell Adhesion MoleculesCells, CulturedEvodiaGlycogen Synthase Kinase 3 betaHumansIndole AlkaloidsMaleMiceMice, Inbred ICRMicrofilament ProteinsNucleotides, CyclicPhosphatidylinositol 3-KinasesPhosphoproteinsPlant ExtractsAlkaloidsCell Adhesion MoleculesGlycogen Synthase Kinase 3 betaGosyuyuIndole AlkaloidsMicrofilament ProteinsNucleotides, CyclicPhosphatidylinositol 3-KinasesPhosphoproteinsPlant ExtractsProto-Oncogene Proteins c-aktQuinazolinesQuinazolinonesQuinolinesrutecarpineVasodilator-Stimulated Phosphoproteincyclic nucleotidehuman plateletshydroxyl radicalMAPKmicrovascular thrombosisPI3K/Akt/GSK3βrutaecarpineVASP

Identifiers

PMID34681769
PMCPMC8537152
OpenAlexW3207804866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.