Evidence map›Paper›PMID 34681712›Full record

ArticleInternational journal of molecular sciences2021

Evidence on the Bioaccessibility of Glucosinolates and Breakdown Products of Cruciferous Sprouts by Simulated In Vitro Gastrointestinal Digestion.

Ángel Abellán, Raúl Domínguez-Perles, Cristina García-Viguera, Diego A Moreno

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

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  14. Current research in food science · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ángel AbellánLaboratory of Phytochemicals and Healthy Foods (LabFAS), Group on Quality, Safety, and Bioactivity of Plant Foods (CEBAS-CSIC), Campus Universitario de Espinardo, 25, 30100 Murcia, Spain.
Raúl Domínguez-PerlesLaboratory of Phytochemicals and Healthy Foods (LabFAS), Group on Quality, Safety, and Bioactivity of Plant Foods (CEBAS-CSIC), Campus Universitario de Espinardo, 25, 30100 Murcia, Spain.ORCID 0000-0001-6232-712X
Cristina García-VigueraLaboratory of Phytochemicals and Healthy Foods (LabFAS), Group on Quality, Safety, and Bioactivity of Plant Foods (CEBAS-CSIC), Campus Universitario de Espinardo, 25, 30100 Murcia, Spain.ORCID 0000-0002-4751-3917
Diego A MorenoLaboratory of Phytochemicals and Healthy Foods (LabFAS), Group on Quality, Safety, and Bioactivity of Plant Foods (CEBAS-CSIC), Campus Universitario de Espinardo, 25, 30100 Murcia, Spain.ORCID 0000-0002-6547-8764
Centro de Edafología y Biología Aplicada del Segura · ES

Funding

Fundación Seneca 20855/PI/18
6 · The paper itself

Abstract

Cruciferous vegetables are gaining importance as nutritious and sustainable foods, rich in phytochemical compounds such as glucosinolates (GSLs). However, the breakdown products of these sulfur-based compounds, mainly represented by isothiocyanates (ITC) and indoles, can contribute to human health. In the human digestive system, the formation of these compounds continues to varying extents in the different stages of digestion, due to the contact of GSLs with different gastric fluids and enzymes under the physicochemical conditions of the gastrointestinal tract. Therefore, the aim of the present work was to uncover the effect of gastrointestinal digestion on the release of glucosinolates and their transformation into their bioactive counterparts by applying a simulated in vitro static model on a range of brassica (red radish, red cabbage, broccoli, and mustard) sprouts. In this sense, significantly higher bioaccessibility of ITC and indoles from GSLs of red cabbage sprouts was observed in comparison with broccoli, red radish, and mustard sprouts, due to the aliphatic GSLs proportion present in the different sprouts. This indicates that the bioaccessibility of GSLs from

Indexed as

BioaccumulationBrassicaChromatography, High Pressure LiquidDigestionGlucosinolatesHumansIndolesIsothiocyanatesSeedlingsTandem Mass SpectrometryGlucosinolatesindoleIndolesIsothiocyanatesisothiocyanic acidbioaccessibilitybrassicaindolesisothiocyanatessproutssulfur-based compounds

Identifiers

PMID34681712
PMCPMC8539263
OpenAlexW3205997072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.