Evidence map›Paper›PMID 34681598›Full record

ArticleInternational journal of molecular sciences2021

Butyrate Alters Pyruvate Flux and Induces Lipid Accumulation in Cultured Colonocytes.

Anna F Bekebrede, Thirza van Deuren, Walter J J Gerrits, Jaap Keijer, Vincent C J de Boer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Frontiers in immunology · 2023
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anna F BekebredeHuman and Animal Physiology, Wageningen University and Research, 6708 WD Wageningen, The Netherlands.
Thirza van DeurenHuman and Animal Physiology, Wageningen University and Research, 6708 WD Wageningen, The Netherlands.ORCID 0000-0002-4839-9757
Walter J J GerritsAnimal Nutrition Group, Wageningen University and Research, 6708 WD Wageningen, The Netherlands.
Jaap KeijerHuman and Animal Physiology, Wageningen University and Research, 6708 WD Wageningen, The Netherlands.ORCID 0000-0002-9720-7491
Vincent C J de BoerHuman and Animal Physiology, Wageningen University and Research, 6708 WD Wageningen, The Netherlands.
Wageningen University & Research · NL

Funding

Dutch Research Council 14942
6 · The paper itself

Abstract

Butyrate is considered the primary energy source of colonocytes and has received wide attention due to its unique health benefits. Insight into the mechanistic effects of butyrate on cellular and metabolic function relies mainly on research in in-vitro-cultured cells. However, cells in culture differ from those

Indexed as

ButyratesCell Line, TumorColonGlucoseGlycolysisHumansLipid DropletsMitochondriaOxygen ConsumptionPyruvic AcidButyratesGlucosePyruvic Acidbutyrateglucose oxidationmetabolic fluxmetabolite interactionsshort-chain fatty acids

Identifiers

PMID34681598
PMCPMC8539916
OpenAlexW3205888470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.