Evidence map›Paper›PMID 34681579›Full record

ReviewInternational journal of molecular sciences2021

d-Amino Acids and pLG72 in Alzheimer's Disease and Schizophrenia.

Yu-Jung Cheng, Chieh-Hsin Lin, Hsien-Yuan Lane

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Sources and Metabolism of D-Amino Acids and Their Roles as Biomarkers in Kidney Disease: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Review
  3. Review
  4. International journal of molecular sciences · 2025
    Article
  5. Aspartate in the Brain: A Review.Neurochemical research · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Promising Application of D-Amino Acids toward Clinical Therapy.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Yu-Jung ChengDepartment of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung 40402, Taiwan.
Chieh-Hsin LinInstitute of Clinical Medical Science, China Medical University, Taichung 40402, Taiwan.
Hsien-Yuan LaneInstitute of Clinical Medical Science, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0003-2162-8174
Asia University · TWChang Gung University · TWChina Medical University · TW

Funding

Chang Gung Memorial Hospital, Linkou CMRPG8G1391Chang Gung Memorial Hospital, Linkou CMRPG8K1162Chang Gung Memorial Hospital, Linkou CMRPG8K1461China Medical University, Taiwan CMU107-S-25Ministry of Science and Technology, Taiwan 109-2314-B-039 -001Ministry of Science and Technology, Taiwan 109-2314-B-039-039-MY3Ministry of Science and Technology, Taiwan 109-2628-B-182A-002Ministry of Science and Technology, Taiwan 110-2314-B-182A-048Ministry of Science and Technology, Taiwan 110-2622-B039-001Ministry of Science and Technology, Taiwan MOST 108-2410-H-039-009-MY2National Health Research Institutes NHRI-EX109-10731NINational Health Research Institutes NHRI-EX110- 10816NC
6 · The paper itself

Abstract

Numerous studies over the last several years have shown that d-amino acids, especially d-serine, have been related to brain and neurological disorders. Acknowledged neurological functions of d-amino acids include neurotransmission and learning and memory functions through modulating

Indexed as

Alzheimer DiseaseAmino AcidsBrainEarly DiagnosisHumansIntracellular Signaling Peptides and ProteinsMitochondriaPolymorphism, Single NucleotideReceptors, N-Methyl-D-AspartateSchizophreniaAmino AcidsDAOA protein, humanIntracellular Signaling Peptides and ProteinsReceptors, N-Methyl-D-AspartateAlzheimer’s diseased-amino acidspLG72schizophrenia

Identifiers

PMID34681579
PMCPMC8535920
OpenAlexW3206275299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.