Evidence map›Paper›PMID 34681564›Full record

ArticleInternational journal of molecular sciences2021

Therapeutic Effect of an Antibody-Derived Peptide in a

Emerenziana Ottaviano, Elisa Borghi, Laura Giovati, Monica Falleni, Delfina Tosi, Walter Magliani, Giulia Morace, Stefania Conti, Tecla Ciociola

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Harnessing cuproptosis: a new avenue for targeted cancer therapies.Apoptosis : an international journal on programmed cell death · 2025
    Review
  2. Synergistic effects ofFrontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. Pathogens (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Emerenziana OttavianoDepartment of Health Sciences, University of Milan, 20142 Milan, Italy.ORCID 0000-0003-3839-2698
Elisa BorghiDepartment of Health Sciences, University of Milan, 20142 Milan, Italy.ORCID 0000-0002-1893-0455
Laura GiovatiDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-7514-1789
Monica FalleniDepartment of Health Sciences, University of Milan, 20142 Milan, Italy.
Delfina TosiDepartment of Health Sciences, University of Milan, 20142 Milan, Italy.ORCID 0000-0002-6130-2665
Walter MaglianiDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Giulia MoraceDepartment of Health Sciences, University of Milan, 20142 Milan, Italy.
Stefania ContiDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-9973-8352
Tecla CiociolaDepartment of Medicine and Surgery, University of Parma, 43126 Parma, Italy.ORCID 0000-0001-6499-2545
University of Milan · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthetic peptide T11F (TCRVDHRGLTF), with sequence identical to a fragment of the constant region of human IgM, and most of its alanine-substituted derivatives proved to possess a significant candidacidal activity in vitro. In this study, the therapeutic efficacy of T11F, D5A, the derivative most active in vitro, and F11A, characterized by a different conformation, was investigated in

Indexed as

AnimalsCandida albicansCandidiasisDisease Models, AnimalHemocytesHumansImmunoglobulin MLarvaMicrobial ViabilityMothsPeptidesSurvival AnalysisTreatment OutcomeImmunoglobulin MPeptidesantibody-derived peptidesantifungal peptidesGalleria mellonellaimmunomodulatory peptides

Identifiers

PMID34681564
PMCPMC8536055
OpenAlexW3207808398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.