Evidence map›Paper›PMID 34681560›Full record

ReviewInternational journal of molecular sciences2021

Vaccines for Non-Viral Cancer Prevention.

Cristina Bayó, Gerhard Jung, Marta Español-Rego, Francesc Balaguer, Daniel Benitez-Ribas

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Cristina BayóDepartment of Immunology, Fundació Clínic per la Recerca Biomèdica (FCRB), Hospital Clínic Barcelona, University of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-7077-6213
Gerhard JungCentro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Department of Gastroenterology, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Hospital Clínic Barcelona, University of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0003-3675-312X
Marta Español-RegoDepartment of Immunology, Fundació Clínic per la Recerca Biomèdica (FCRB), Hospital Clínic Barcelona, University of Barcelona, 08036 Barcelona, Spain.
Francesc BalaguerCentro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Department of Gastroenterology, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Hospital Clínic Barcelona, University of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-0206-0539
Daniel Benitez-RibasDepartment of Immunology, Fundació Clínic per la Recerca Biomèdica (FCRB), Hospital Clínic Barcelona, University of Barcelona, 08036 Barcelona, Spain.
Fundació Clínic per a la Recerca Biomèdica · ESCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer vaccines are a type of immune therapy that seeks to modulate the host's immune system to induce durable and protective immune responses against cancer-related antigens. The little clinical success of therapeutic cancer vaccines is generally attributed to the immunosuppressive tumor microenvironment at late-stage diseases. The administration of cancer-preventive vaccination at early stages, such as pre-malignant lesions or even in healthy individuals at high cancer risk could increase clinical efficacy by potentiating immune surveillance and pre-existing specific immune responses, thus eliminating de novo appearing lesions or maintaining equilibrium. Indeed, research focus has begun to shift to these approaches and some of them are yielding encouraging outcomes.

Indexed as

Cancer VaccinesHumansNeoplasmsNeoplasm StagingPrecancerous ConditionsTumor MicroenvironmentCancer Vaccinescancerdendritic cellsLynch syndromepreventionvaccines

Identifiers

PMID34681560
PMCPMC8535337
OpenAlexW3203028472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.