Evidence map›Paper›PMID 34681530›Full record

ArticleFoods (Basel, Switzerland)2021

Comparative

Angela I Wann, Benita C Percival, Katy Woodason, Miles Gibson, Siâny Vincent, Martin Grootveld

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. High-resolutionJournal of food and drug analysis · 2023
    Article
  5. Article
  6. Molecules (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Angela I WannLeicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Benita C PercivalLeicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.ORCID 0000-0002-8769-8979
Katy WoodasonLeicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Miles GibsonLeicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Siâny VincentLeicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.
Martin GrootveldLeicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK.ORCID 0000-0003-1502-3734
De Montfort University · GBKingston University · GB

Funding

Weston A. Price Foundation WP2-MG5
6 · The paper itself

Abstract

Soybean oil is the second most exported oil from the United States and South America, and is widely marketed as a cooking oil product containing numerous health benefits for human consumers. However, culinary oils with high polyunsaturated fatty acid (PUFA) contents, are known to produce high quantities of lipid oxidation products (LOPs), including toxic aldehydes upon exposure to high-temperature frying episodes. Previous studies have demonstrated causal links between aldehyde ingestion and inhalation with deleterious health perturbations, including mutagenic and carcinogenic effects, along with cardiovascular and teratogenic actions. In this study, aldehydic LOPs were detected and quantified in commercially available samples of soybean, avocado, corn and extra-virgin olive oil products before and after their exposure to laboratory-simulated laboratory frying episodes (LSSFEs) using high-resolution 1H nuclear magnetic resonance (NMR) analysis. Results acquired demonstrated that PUFA-rich soybean and corn oils gave rise to the highest concentrations of oil aldehydes from the thermo-oxidation of unsaturated fatty acids, whereas monounsaturated fatty acid (MUFA)-laden avocado and olive oils were much more resistant to this peroxidation process, as expected. Multivariate chemometrics analyses provided evidence that an orthogonal component pattern of aldehydic LOPs featuring low-molecular-mass n-alkanals such as propanal, and 4-oxo-alkanals, arises from thermo-oxidation of the ω-3 fatty acid (FA) linolenic acid (present in soybean oils at levels of ca. 7% (

Indexed as

1H NMR analysis4-Oxo-n-alkanalsaldehydeschemometrics analysisfood toxicologyfrying oilshigh-temperature frying practiceslipid oxidation productslow-molecular-mass n-alkanalssoybean oilω-3 fatty acids

Identifiers

PMID34681530
PMCPMC8535530
OpenAlexW3205693886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.