ArticleFoods (Basel, Switzerland)2021
Effects of Tartary Buckwheat Protein on Gut Microbiome and Plasma Metabolite in Rats with High-Fat Diet.
Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Systematic Review of Human and Animal Evidence on the Role of Buckwheat Consumption on Gastrointestinal Health.Nutrients · 2022Pooled it
- A Narrative Review on Pseudocereals and Cardiometabolic Health: Biological Mechanisms and Evidence from Human Studies.Nutrients · 2026Review
- Effects of dietary glutamine supplementation on lipid metabolism, fatty acid composition, and taste properties in the longissimus thoracis muscle of feed-restricted yaks.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Nanovesicles fromPharmaceuticals (Basel, Switzerland) · 2025Article
- Fabrication and Mechanism of Pickering Emulsions Stability over a Broad pH Range Using Tartary Buckwheat Protein-Sodium Alginate Composite Particles.Foods (Basel, Switzerland) · 2025Article
- Enzymes (α-Amylase, Xylanase, and Cellulase) in Steamed Buckwheat Buns: The Effects on Quality and Predicted Glycemic Response.Foods (Basel, Switzerland) · 2025Article
- The Chemical Constituents and Anti-Hyperlipidemia Effect of Salt-Processed Fenugreek Seed.Food science & nutrition · 2025Article
- Tartary Buckwheat Bran and Fructus Aurantii Combination (TBB-FA): A Promising Therapeutic Approach for Functional Dyspepsia via Modulation of Gut Microbiota, Short-Chain Fatty Acids and Purine Signaling Pathway.Food science & nutrition · 2025Article
- Microbial Fermentation Enhances the Effect of Black Tea on Hyperlipidemia by Mediating Bile Acid Metabolism and Remodeling Intestinal Microbes.Nutrients · 2024Article
- Effect ofHeliyon · 2024Article
- Functional Ingredients in Minor Grain Crops.Foods (Basel, Switzerland) · 2023Article
- Dietary-Derived Exosome-like Nanoparticles as Bacterial Modulators: Beyond MicroRNAs.Nutrients · 2023Review
- Tartary Buckwheat (Foods (Basel, Switzerland) · 2022Article
- Effect of the Addition of Buckwheat Sprouts Modified with the Addition ofMolecules (Basel, Switzerland) · 2022Article
- Antioxidant and anti-obesity effects of in vitro digesta of germinated buckwheat.Food science and biotechnology · 2022Article
- Gut microbiota signature as predictors of adverse outcomes after acute ischemic stroke in patients with hyperlipidemia.Frontiers in cellular and infection microbiology · 2022Article
- Wheat supplement with buckwheat affect gut microbiome composition and circulate short-chain fatty acids.Frontiers in nutrition · 2022Article
- Variations in the fecal microbiota and their functions of Thoroughbred, Mongolian, and Hybrid horses.Frontiers in veterinary science · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The prevalence of lipid metabolism diseases, mainly obesity, fatty liver, and hyperlipidemia, is increasing in the world. Tartary buckwheat is a kind of medicinal and edible crop, and clinical experiments have also confirmed that dietary Tartary buckwheat can effectively regulate lipid metabolism disorders. Tartary buckwheat protein (TBP), as the main active ingredient of Tartary buckwheat, has an effect of blood lipid reduction that has been widely reported. In this paper, we investigated the constituents of TBP and then evaluated the hypolipidemic effect of TBP in hyperlipidemia rats. Male Sprague-Dawley rats were fed a high-fat diet for six weeks to induce hyperlipidemia and then given TBP orally for five weeks. The effects of TBP on body weight, serum lipids, liver lipids, liver oxidative stress, pathological organization, gut microbiota, and plasma metabolites were analyzed. At the serum level, TBP supplement significantly decrease the level of LDL-C and increase the level of HDL-C. At the liver level, it can reduce the levels of TC, TG, and LDL-C. The potential mechanism of action is, on the one hand, to increase the abundance of the Lachnospiraceae and the Ruminococcaceae by modulating the gut microbiota, facilitating the productivity of short-chain fatty acids, and increasing fecal bile acid excretion and, on the other hand, may be related to the improvement of bile acid metabolism.
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