Evidence map›Paper›PMID 34681359›Full record

ArticleFoods (Basel, Switzerland)2021

Maintaining the Balance of Intestinal Flora through the Diet: Effective Prevention of Illness.

Li Zhang, Zhenying Zhang, Lei Xu, Xin Zhang

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Microbiome-guided cancer immunotherapy: immune mechanisms, resistance pathways, and translational opportunities for precision oncology.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  3. Metagenomic Insights into Gut Microbiota Alterations FollowingInternational journal of molecular sciences · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Foods (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Postbiotics fromFoods (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Review
  15. Effects ofFoods (Basel, Switzerland) · 2022
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Li ZhangDepartment of Physical Education, China University of Mining and Technology, Beijing 100083, China.
Zhenying ZhangDepartment of Physical Education, China University of Mining and Technology, Beijing 100083, China.
Lei XuDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.
Xin ZhangDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, China.ORCID 0000-0002-5795-9197

Funding

Fundamental Research Funds for the Central Universities 2020SKTY01
6 · The paper itself

Abstract

The human body is home to a complex community of dynamic equilibrium microbiota, including bacteria, fungi, parasites, and viruses. It is known that the gut microbiome plays a crucial role in regulating innate and adaptive immune responses, intestinal peristalsis, intestinal barrier homeostasis, nutrient uptake, and fat distribution. The complex relationship between the host and microbiome suggests that when this relationship is out of balance, the microbiome may contribute to disease development. The brain-gut-microbial axis is composed of many signal molecules, gastrointestinal mucosal cells, the vagus nerve, and blood-brain barrier, which plays an essential role in developing many diseases. The microbiome can influence the central nervous system function through the brain-gut axis; the central nervous system can also affect the composition and partial functions of the gut microbiome in the same way. Different dietary patterns, specific dietary components, and functional dietary factors can significantly affect intestinal flora's structure, composition, and function, thereby affecting human health. Based on the above, this paper reviewed the relationship between diet, intestinal flora, and human health, and the strategies to prevent mental illness through the dietary modification of intestinal microorganisms.

Indexed as

brain–gut–microbial axisdietarygut microbiomemental illness

Identifiers

PMID34681359
PMCPMC8534928

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.