Evidence map›Paper›PMID 34681267›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Ten-Year Outcomes of Intravitreal Bevacizumab for Myopic Choroidal Neovascularization: Analysis of Prognostic Factors.

Fabiana Mallone, Rosalia Giustolisi, Federica Franzone, Marco Marenco, Rocco Plateroti, Marcella Nebbioso, Alessandro Lambiase, Magda Gharbiya

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fabiana MalloneDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-6274-015X
Rosalia GiustolisiDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.
Federica FranzoneDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-2548-7807
Marco MarencoDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-6978-3790
Rocco PlaterotiDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.
Marcella NebbiosoDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-5512-0849
Alessandro LambiaseDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-8974-991X
Magda GharbiyaDepartment of Organ of Sense, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-4991-9689
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current standard treatment of myopic choroidal neovascularisation (mCNV) is intravitreal injection of VEGF antagonists. This study was proposed to assess efficacy and safety of intravitreal bevacizumab (IVB) for the treatment of mCNV across a 10-year follow-up. Thirty eyes of thirty patients with treatment-naïve mCNV who underwent IVB and were followed up with for a minimum of ten years were recruited for the present retrospective cohort study. All participants were treated with three monthly IVB at baseline and then evaluated and treated under pro re nata (PRN) schedule. Outcome measures were to determine BCVA changes over years and identify the predictive factors of both final visual outcome and need for retreatment. Analysis of the main involved prognostic factors with correlations among variables is reported. Visual acuity remained stable at 10-year follow-up (

Indexed as

bevacizumab (IVB)drug delivery systemslong-term resultsmyopic choroidal neovascularization (mCNV)ocular pharmacologyophthalmologypathologic myopia (PM)

Identifiers

PMID34681267
PMCPMC8541117
OpenAlexW3205975262

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.