Evidence map›Paper›PMID 34681235›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Zinc Binding to NAP-Type Neuroprotective Peptides: Nuclear Magnetic Resonance Studies and Molecular Modeling.

Ancuta-Veronica Lupaescu, Cosmin Stefan Mocanu, Gabi Drochioiu, Catalina-Ionica Ciobanu

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ancuta-Veronica LupaescuIntegrated Center for Research, Development and Innovation in Advanced Materials, Nanotechnologies and Distributed Systems for Fabrication and Control (MANSiD), Stefan cel Mare University of Suceava, 720229 Suceava, Romania.
Cosmin Stefan MocanuFaculty of Chemistry, Alexandru Ioan Cuza University, 11 Carol I, 700506 Iasi, Romania.
Gabi DrochioiuFaculty of Chemistry, Alexandru Ioan Cuza University, 11 Carol I, 700506 Iasi, Romania.ORCID 0000-0002-5506-0313
Catalina-Ionica CiobanuCERNESIM Centre, Institute of Interdisciplinary Research, Alexandru Ioan Cuza University of Iasi, 11 Carol I, 700506 Iasi, Romania.ORCID 0000-0002-4264-9049
Alexandru Ioan Cuza University · ROŞtefan cel Mare University of Suceava · RO

Funding

The Ministry of Research, Innovation and Digitization, CNCS/CCCDI-UEFISCDI project number: CNFIS-FDI-2021-0501
6 · The paper itself

Abstract

Aggregation of amyloid-β peptides (Aβ) is a hallmark of Alzheimer's disease (AD), which is affecting an increasing number of people. Hence, there is an urgent need to develop new pharmaceutical treatments which could be used to prevent the AD symptomatology. Activity-dependent neuroprotective protein (ADNP) was found to be deficient in AD, whereas NAP, an 8-amino-acid peptide (

Indexed as

Alzheimer’s diseasemolecular modelingNAP-type peptidesneuroprotectionNMR spectroscopyzinc binding

Identifiers

PMID34681235
PMCPMC8541368
OpenAlexW3203304232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.