Evidence map›Paper›PMID 34681170›Full record

ReviewPharmaceuticals (Basel, Switzerland)2021

Novel Delivery Systems of Polyphenols and Their Potential Health Benefits.

Bianca Enaru, Sonia Socaci, Anca Farcas, Carmen Socaciu, Corina Danciu, Andreea Stanila, Zorita Diaconeasa

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Article
  3. Polyphenol-Loaded Liposomal Nanocarriers fromMolecules (Basel, Switzerland) · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Interaction ofJournal of functional biomaterials · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bianca EnaruDepartment of Food Science and Technology, Faculty of Food Science and Technology, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Sonia SocaciDepartment of Food Science and Technology, Faculty of Food Science and Technology, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0003-0594-4628
Anca FarcasDepartment of Food Science and Technology, Faculty of Food Science and Technology, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-1392-4080
Carmen SocaciuDepartment of Food Science and Technology, Faculty of Food Science and Technology, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-7352-5057
Corina DanciuDepartment of Pharmacognosy, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Andreea StanilaDepartment of Food Science and Technology, Faculty of Food Science and Technology, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0003-2739-7565
Zorita DiaconeasaDepartment of Food Science and Technology, Faculty of Food Science and Technology, University of Agricultural Science and Veterinary Medicine, 400372 Cluj-Napoca, Romania.ORCID 0000-0002-5325-3859
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · ROVictor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

Romanian Ministry of Education and Research, CNCS - UEFISCDI PN-III-P4-ID-PCE-2020-1847 and PN-III-P4-ID-PCE-2020-2306, within PNCDI II
6 · The paper itself

Abstract

Liposome-based delivery systems have been studied and used more frequently in recent years due to their advantages, such as low toxicity, specificity, and the ability to protect the encapsulated substance from environmental factors, which could otherwise degrade the active compound and reduce its effectiveness. Given these benefits, many researchers have encapsulated polyphenols in liposomes, thus increasing their bioavailability and stability. Similarly, polyphenols encapsulated in liposomes are known to produce more substantial effects on targeted cells than unencapsulated polyphenols, while having minimal cytotoxicity in healthy cells. Although polyphenols play a role in preventing many types of disease and generally have beneficial effects on health, we solely focused on their chemopreventive effects on cancer through liposomes in this review. Our goal was to summarize the applicability and efficacy of liposomes encapsulated with different classes of polyphenols on several types of cancer, thus opening the opportunity for future studies based on these drug delivery systems.

Indexed as

cancer therapychemopreventionhealthliposomespolyphenols

Identifiers

PMID34681170
PMCPMC8538464
OpenAlexW3201431827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.