Evidence map›Paper›PMID 34680972›Full record

Trial reportGenes2021

COVID-19 Infection Alters the Microbiome: Elite Athletes and Sedentary Patients Have Similar Bacterial Flora.

Gergely Babszky, Ferenc Torma, Dora Aczel, Peter Bakonyi, Zoltan Gombos, Janos Feher, Dóra Szabó, Balázs Ligeti, Sándor Pongor, Laszlo Balogh and 2 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Exercise perspective: Benefits and mechanisms of gut microbiota on the body.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Gergely BabszkyResearch Institute of Sport Science, University of Physical Education, 1123 Budapest, Hungary.
Ferenc TormaResearch Institute of Sport Science, University of Physical Education, 1123 Budapest, Hungary.
Dora AczelResearch Institute of Sport Science, University of Physical Education, 1123 Budapest, Hungary.
Peter BakonyiResearch Institute of Sport Science, University of Physical Education, 1123 Budapest, Hungary.ORCID 0000-0002-6120-3384
Zoltan GombosResearch Institute of Sport Science, University of Physical Education, 1123 Budapest, Hungary.
Janos FeherDepartment of Ophthalmology, Sapienza University of Rome, 00185 Rome, Italy.
Dóra SzabóInstitute of Medical Microbiology, Semmelweis University, 1123 Budapest, Hungary.
Balázs LigetiFaculty of Information Technology and Bionics, Pázmány Péter Catholic University, 1123 Budapest, Hungary.
Sándor PongorFaculty of Information Technology and Bionics, Pázmány Péter Catholic University, 1123 Budapest, Hungary.
Laszlo BaloghInstitute of Sport Science, University of Debrecen, 4000 Debrecen, Hungary.
Anikó PósaInterdisciplinary Excellence Center, Department of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, 6700 Szeged, Hungary.
Zsolt RadakResearch Institute of Sport Science, University of Physical Education, 1123 Budapest, Hungary.ORCID 0000-0003-1297-6804
Hungarian University of Sports Science · HUPázmány Péter Catholic University · HUSapienza University of Rome · ITSemmelweis University · HUUniversity of Debrecen · HUUniversity of Szeged · HUWaseda University · JP

Funding

Innovation and Technology Ministry, Hungary Scientific Excellence Program TKP2020-NKA-17
6 · The paper itself

Abstract

Regular exercise can upgrade the efficiency of the immune system and beneficially alter the composition of the gastro-intestinal microbiome. We tested the hypothesis that active athletes have a more diverse microbiome than sedentary subjects, which could provide better protection against COVID-19 during infection. Twenty active competing athletes (CA) (16 male and 4 females of the national first and second leagues), aged 24.15 ± 4.7 years, and 20 sedentary subjects (SED) (15 male and 5 females), aged 27.75 ± 7.5 years, who had been diagnosed as positive for COVID-19 by a PCR test, served as subjects for the study. Fecal samples collected five to eight days after diagnosis and three weeks after a negative COVID-19 PCR test were used for microbiome analysis. Except for two individuals, all subjects reported very mild and/or mild symptoms of COVID-19 and stayed at home under quarantine. Significant differences were not found in the bacterial flora of trained and untrained subjects. On the other hand, during COVID-19 infection, at the phylum level, the relative abundance of

Indexed as

AthletesGastrointestinal MicrobiomeSedentary BehaviorAdultBacteroidetesCOVID-19FemaleHumansMaleSARS-CoV-2BacteroidetesCOVID-19exerciseinflammationmicrobiome

Identifiers

PMID34680972
PMCPMC8536180
OpenAlexW3203825068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.