Evidence map›Paper›PMID 34680890›Full record

ArticleGenes2021

Genome-Wide Association Studies for Milk Somatic Cell Score in Romanian Dairy Cattle.

Daniela Elena Ilie, Alexandru Eugeniu Mizeranschi, Ciprian Valentin Mihali, Radu Ionel Neamț, George Vlad Goilean, Ovidiu Ionuț Georgescu, Daniela Zaharie, Mihai Carabaș, Ioan Huțu

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Daniela Elena IlieThe Molecular Research Department, Research and Development Station for Bovine Arad, Bodrogului Street, No. 32, 310059 Arad, Romania.
Alexandru Eugeniu MizeranschiThe Molecular Research Department, Research and Development Station for Bovine Arad, Bodrogului Street, No. 32, 310059 Arad, Romania.
Ciprian Valentin MihaliThe Molecular Research Department, Research and Development Station for Bovine Arad, Bodrogului Street, No. 32, 310059 Arad, Romania.
Radu Ionel NeamțThe Molecular Research Department, Research and Development Station for Bovine Arad, Bodrogului Street, No. 32, 310059 Arad, Romania.
George Vlad GoileanThe Molecular Research Department, Research and Development Station for Bovine Arad, Bodrogului Street, No. 32, 310059 Arad, Romania.
Ovidiu Ionuț GeorgescuFaculty of Veterinary Medicine, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.
Daniela ZaharieFaculty of Mathematics and Computer Science, West University of Timișoara, 300223 Timisoara, Romania.
Mihai CarabașFaculty of Automatic Control and Computer Science, Politehnica University of Bucharest, 060042 București, Romania.
Ioan HuțuFaculty of Veterinary Medicine, Banat's University of Agricultural Sciences and Veterinary Medicine "King Michael I of Romania" from Timisoara, Calea Aradului No. 119, 300645 Timisoara, Romania.
Arad County Clinical Hospital · ROUnivesity of Life Science "King Mihai I" from Timisoara · ROUniversitatea Națională de Știință și Tehnologie Politehnica București · ROWest University of Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastitis is one of the most frequently encountered diseases in dairy cattle, negatively affecting animal welfare and milk production. For this reason, contributions to understanding its genomic architecture are of great interest. Genome-wide association studies (GWAS) have identified multiple loci associated with somatic cell score (SCS) and mastitis in cattle. However, most of the studies have been conducted in different parts of the world on various breeds, and none of the investigations have studied the genetic architecture of mastitis in Romanian dairy cattle breeds up to this point in time. In this study, we report the first GWAS for SCS in dairy cattle breeds from Romania. For GWAS, we used an Axiom Bovine v3 SNP-chip (>63,000 Single Nucleotide Polymorphism -SNPs) and 33,330 records from 690 cows belonging to Romanian Spotted (RS) and Romanian Brown (RB) cattle. The results found one SNP significantly associated with SCS in the RS breed and 40 suggestive SNPs with -log

Indexed as

Genetic Predisposition to DiseaseAnimalsCattleFemaleGenome-Wide Association StudyGenotypeLactationMastitis, BovineMilkPhenotypePolymorphism, Single NucleotidePregnancyQuantitative Trait LociRomaniaUbiquitin-Protein LigasesUbiquitin-Protein Ligasesgenome-wide association study (GWAS)mastitisRomanian cattlesomatic cell score

Identifiers

PMID34680890
PMCPMC8535694
OpenAlexW3202851423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.