Evidence map›Paper›PMID 34680886›Full record

ArticleGenes2021

A Single Base Insertion in

Henrike Kuder, Liubov Sandzhieva-Vuzzo, Alexandra Kehl, Jonathan M Rappaport, Elisabeth Müller, Urs Giger

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Henrike KuderLaboklin GmbH & Co. KG (Labogen), Steubenstraße 4, D-97688 Bad Kissingen, Germany.ORCID 0000-0002-4138-5782
Liubov Sandzhieva-VuzzoAdvanced Veterinary Care Center, 8920 W. State Road 84, Davie, FL 33324, USA.
Alexandra KehlLaboklin GmbH & Co. KG (Labogen), Steubenstraße 4, D-97688 Bad Kissingen, Germany.ORCID 0000-0002-1547-0713
Jonathan M RappaportAdvanced Veterinary Care Center, 8920 W. State Road 84, Davie, FL 33324, USA.
Elisabeth MüllerLaboklin GmbH & Co. KG (Labogen), Steubenstraße 4, D-97688 Bad Kissingen, Germany.
Urs GigerVetsuisse Faculty, University of Zürich, Winterthurerstrasse 260, CH-8057 Zürich, Switzerland.ORCID 0000-0002-4770-4107
Laboklin (Germany) · DEUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophilia B is an x-linked recessive hereditary coagulopathy that has been reported in various species. We describe a male Newfoundland-Parti Standard Poodle hybrid puppy and its family with hemophilia B from clinical manifestations to the molecular genetic defect. The index case presented for dyspnea was found to have a mediastinal hematoma, while surgical removal and transfusion support brought some relief, progressive hematoma formations led to humane euthanasia. Sequencing the

Indexed as

Genetic Predisposition to DiseaseAnimalsDog DiseasesDogsExonsFactor IXFemaleGenes, X-LinkedHemophilia BMaleMutagenesis, InsertionalPedigreeFactor IXbleeding disordercaninecoagulopathyfactor IXframeshift mutationintrinsic pathwaypartial thromboplastin timeX-linked recessive

Identifiers

PMID34680886
PMCPMC8535623
OpenAlexW3204203080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.