Evidence map›Paper›PMID 34680851›Full record

ArticleAntibiotics (Basel, Switzerland)2021

The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37.

David A Perez-Perez, Teresa de J Villanueva-Ramirez, Adriana E Hernandez-Pedraza, Nestor G Casillas-Vega, Patricia Gonzalez-Barranco, Xristo Zarate

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  6. The future of recombinant host defense peptides.Microbial cell factories · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

David A Perez-PerezUniversidad Autonoma de Nuevo Leon, Facultad de Ciencias Quimicas, Av. Universidad s/n, Cd. Universitaria, San Nicolas de los Garza 66455, Mexico.
Teresa de J Villanueva-RamirezUniversidad Autonoma de Nuevo Leon, Facultad de Ciencias Quimicas, Av. Universidad s/n, Cd. Universitaria, San Nicolas de los Garza 66455, Mexico.
Adriana E Hernandez-PedrazaCHRISTUS-LATAM HUB Center of Excellence and Innovation, S.C., Lazaro Cardenas 2321, San Pedro Garza Garcia 66260, Mexico.
Nestor G Casillas-VegaUniversidad Autonoma de Nuevo Leon, Departamento de Patologia Clinica, Hospital Universitario Dr. Jose Eleuterio Gonzalez, Monterrey 64460, Mexico.
Patricia Gonzalez-BarrancoUniversidad Autonoma de Nuevo Leon, Facultad de Ciencias Quimicas, Av. Universidad s/n, Cd. Universitaria, San Nicolas de los Garza 66455, Mexico.ORCID 0000-0001-8832-4891
Xristo ZarateUniversidad Autonoma de Nuevo Leon, Facultad de Ciencias Quimicas, Av. Universidad s/n, Cd. Universitaria, San Nicolas de los Garza 66455, Mexico.ORCID 0000-0002-9824-3961
Universidad Autónoma de Nuevo León · MX

Funding

Universidad Autonoma de Nuevo Leon UANL-PAICYT-CN942-19 and CN-1722-21
6 · The paper itself

Abstract

(1) Background: The cathelicidin peptide LL-37 is a prominent molecule with many biological activities, including antimicrobial. Due to its importance, here, we describe the production of LL-37 tagged with SmbP, a relatively new carrier protein that improves the production of recombinant proteins and peptides in

Indexed as

antimicrobial peptidesEscherichia coliLL-37recombinant peptidessmall metal-binding proteinSmbPStaphylococcus aureus

Identifiers

PMID34680851
PMCPMC8532731
OpenAlexW3207699057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.