Evidence map›Paper›PMID 34680843›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Equisetin Restores Colistin Sensitivity against Multi-Drug Resistant Gram-Negative Bacteria.

Qi Zhang, Shang Chen, Xiaojia Liu, Wenhan Lin, Kui Zhu

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Fingolimod synergizes and reversesFrontiers in microbiology · 2024
    Article
  9. Review
  10. Article
  11. β-Lactams from the Ocean.Marine drugs · 2023
    Review
  12. Article
  13. Article
  14. Synergistic Activity of Tetrandrine and Colistin againstAntibiotics (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qi ZhangNational Center for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Shang ChenNational Center for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-4874-2922
Xiaojia LiuNational Center for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Wenhan LinState Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.ORCID 0000-0002-4978-4083
Kui ZhuNational Center for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
China Agricultural University · CNPeking University · CN

Funding

Chinese Universities Scientific Fund 2021TC058National Natural Science Foundation of China 21861142006National Natural Science Foundation of China 31922083 357
6 · The paper itself

Abstract

The overuse of antibiotics and the scarcity of new drugs have led to a serious antimicrobial resistance crisis, especially for multi-drug resistant (MDR) Gram-negative bacteria. In the present study, we investigated the antimicrobial activity of a marine antibiotic equisetin in combination with colistin against Gram-negative bacteria and explored the mechanisms of synergistic activity. We tested the synergistic effect of equisetin in combination with colistin on 23 clinical

Indexed as

antimicrobial resistancecolistindrug combinationequisetinGram-negative bacteria

Identifiers

PMID34680843
PMCPMC8532683
OpenAlexW3206519598

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.