Evidence map›Paper›PMID 34680821›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Daily Administered Dual-Light Photodynamic Therapy Provides a Sustained Antibacterial Effect on

Sakari Nikinmaa, Anna Podonyi, Peter Raivio, Jukka Meurman, Timo Sorsa, Juha Rantala, Esko Kankuri, Tuomas Tauriainen, Tommi Pätilä

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05720104 nawithdrawnnot on this mapstarted 2023, after this paper: background citation

Effect of Regular Antibacterial Photodynamic Therapy on Oral Hygiene in the Elderly 24-hour Care Residents

TypeinterventionalSponsorKoite Health OyRan2023 to 2026Enrolled0ConditionsInflamed Gums, Dryness Oral, PlaqueArmsLumoral Treatment, Standard oral hygiene instructions
NCT06859866 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Adjunctive At-Home Photodynamic Therapy (aPDT) in the Treatment of Peri-Implant Mucositis: A Post-Marketing Interventional Pilot Study With a Medical Device

TypeinterventionalSponsorKoite Health OyRan2025 to 2027Enrolled30ConditionsPeri-implant MucositisArmsStandard oral hygiene, The addition of home-based dual-light photodynamic therapy (Lumorinse® + Lumoral®)
NCT06860321 nacompletednot on this mapstarted 2025, after this paper: background citation

Photodynamic Treatment in the Management of Residual Biofilm - a Crossover Study

TypeinterventionalSponsorKoite Health OyRan2025 to 2025Enrolled20ConditionsHealthy Adults, Plaque, DentalArmsAdjunct antibacterial home-use dual-light medical device, Regular oral self care
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Peri-Implant Diseases: Enhanced Antibacterial Photodynamic Therapy.Clinical and experimental dental research · 2025
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Sakari NikinmaaDepartment of Neuroscience and Biomedical Engineering, Aalto University, 02150 Espoo, Finland.
Anna PodonyiDepartment of Cardiac Surgery, University Hospital Southampton, Southampton SO16 6YD, Hampshire, UK.ORCID 0000-0003-2226-1730
Peter RaivioHeart and Lung Center, Meilahti Hospital, 00290 Helsinki, Finland.
Jukka MeurmanDepartment of Oral and Maxillofacial Diseases, University of Helsinki, 00290 Helsinki, Finland.
Timo SorsaDepartment of Oral and Maxillofacial Diseases, University of Helsinki, 00290 Helsinki, Finland.
Juha RantalaKoite Health Oy, 02150 Espoo, Finland.
Esko KankuriDepartment of Pharmacology, University of Helsinki, 00290 Helsinki, Finland.ORCID 0000-0002-2193-8773
Tuomas TauriainenHeart and Lung Center, Meilahti Hospital, 00290 Helsinki, Finland.
Tommi PätiläDepartment of Neuroscience and Biomedical Engineering, Aalto University, 02150 Espoo, Finland.
University of Helsinki · FIAalto University · FIHerttoniemi Hospital · FIUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

Instrumentarium Science Foundation No grant number available
6 · The paper itself

Abstract

New means to reduce excessive antibiotic use are urgently needed. This study tested dual-light aPDT against

Indexed as

antibacterial photodynamic therapybiofilmStaphylococcus aureus

Identifiers

PMID34680821
PMCPMC8533018
OpenAlexW3206572200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.