ReviewAntibiotics (Basel, Switzerland)2021
Is Penicillin Allergy a Risk Factor for Early Dental Implant Failure? A Systematic Review.
Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Is clindamycin effective in preventing infectious complications after oral surgery? Systematic review and meta-analysis of randomized controlled trials.Clinical oral investigations · 2022Pooled it
- The effect of preoperative clindamycin in reducing early oral implant failure: a randomised placebo-controlled clinical trial.Clinical oral investigations · 2023Trial
- Survival and Risk Factors of Implants Placed in Sites of Previous Failures-A Nationwide Retrospective Cohort Study.Journal of clinical periodontology · 2026Article
- Failure of Wide-Diameter Dental Implants (Predominantly 5.0 mm) Show Distinct Risk Profiles-A Large Cohort Study.Clinical implant dentistry and related research · 2026Article
- Self-Reported Penicillin Allergy, Alternative Antibiotics, and Implant Outcomes: A Retrospective Study.Clinical implant dentistry and related research · 2026Article
- Early dental implant outcomes in patients with reported penicillin allergy: a retrospective study on clindamycin safety.BMC oral health · 2026Article
- Marginal bone loss and associated factors in immediate dental implants: a retrospective clinical study.International journal of implant dentistry · 2025Article
- Is Antibiotic Prophylaxis Necessary before Dental Implant Procedures in Patients with Orthopaedic Prostheses? A Systematic Review.Antibiotics (Basel, Switzerland) · 2022Review
- Preventive Antibiotic Therapy in the Placement of Immediate Implants: A Systematic Review.Antibiotics (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prescription of preventive antibiotics in dental implant treatments reduces the incidence of early failures. This study has focused mainly on the influence of amoxicillin, which is contraindicated in penicillin-allergic patients. The present systematic review aimed to determine whether penicillin-allergic patients have a higher risk of implant failure compared to non-allergic patients. An electronic search was performed on Medline and Web of Science using the following MeSH terms: (penicillin allergy OR clindamycin OR erythromycin OR azithromycin OR metronidazole) AND (dental implant OR dental implant failure OR dental implant complications). The criteria employed were those described in the PRISMA
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.