Evidence map›Paper›PMID 34680767›Full record

ArticleAntibiotics (Basel, Switzerland)2021

An Enzybiotic Regimen for the Treatment of Methicillin-Resistant

Eric T Sumrall, Marloes I Hofstee, Daniel Arens, Christian Röhrig, Susanne Baertl, Dominic Gehweiler, Mathias Schmelcher, Martin J Loessner, Stephan Zeiter, R Geoff Richards and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  4. Acta pharmaceutica Sinica. B · 2024
    Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Eric T SumrallAO Research Institute Davos, 7270 Davos, Switzerland.
Marloes I HofsteeAO Research Institute Davos, 7270 Davos, Switzerland.
Daniel ArensAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0002-2705-0812
Christian RöhrigMicreos GmbH, 8820 Wädenswil, Switzerland.ORCID 0000-0003-4647-1011
Susanne BaertlAO Research Institute Davos, 7270 Davos, Switzerland.
Dominic GehweilerAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0001-7148-9569
Mathias SchmelcherMicreos GmbH, 8820 Wädenswil, Switzerland.ORCID 0000-0003-3535-3861
Martin J LoessnerInstitute of Food, Nutrition and Health, ETH Zürich, 8092 Zurich, Switzerland.
Stephan ZeiterAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0002-8155-4202
R Geoff RichardsAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0002-7778-2480
T Fintan MoriartyAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0003-2307-0397
AO Foundation · CHETH Zurich · CH

Funding

AO Foundation AOTrauma
6 · The paper itself

Abstract

Orthopaedic device-related infection (ODRI) presents a significant challenge to the field of orthopaedic and trauma surgery. Despite extensive treatment involving surgical debridement and prolonged antibiotic therapy, outcomes remain poor. This is largely due to the unique abilities of

Indexed as

biofilmendolysinenzybioticfracture-related infectionMRSAorthopaedic infectionosteomyelitisStaphylococcus aureus

Identifiers

PMID34680767
PMCPMC8533017
OpenAlexW3202597609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.