Evidence map›Paper›PMID 34680575›Full record

ArticleBiomedicines2021

Differential Capability of Clinically Employed Dermal Regeneration Scaffolds to Support Vascularization for Tissue Bioengineering.

Chiara Agostinis, Mariagiulia Spazzapan, Roman Vuerich, Andrea Balduit, Chiara Stocco, Alessandro Mangogna, Giuseppe Ricci, Giovanni Papa, Serena Zacchigna, Roberta Bulla

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Investigation of the Properties of Linen Fibers and Dressings.International journal of molecular sciences · 2022
    Article
  8. Article
  9. Gender Affirming Revision Vaginoplasty Utilizing Decellularized Fish Skin Xenograft: Surgical Technique and Outcomes.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chiara AgostinisInstitute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "Burlo Garofolo", 34137 Trieste, Italy.
Mariagiulia SpazzapanDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-4338-0942
Roman VuerichDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Andrea BalduitDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-5902-3205
Chiara StoccoDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34100 Trieste, Italy.
Alessandro MangognaInstitute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0001-7910-1274
Giuseppe RicciInstitute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-8031-1102
Giovanni PapaDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34100 Trieste, Italy.ORCID 0000-0003-4676-2775
Serena ZacchignaInternational Centre for Genetic Engineering and Biotechnology, Cardiovascular Biology Laboratory, 34149 Trieste, Italy.
Roberta BullaDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0003-1737-5776
University of Trieste · ITIRCCS Materno Infantile Burlo Garofolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The loss of skin integrity has always represented a major challenge for clinicians dealing with dermal defects, such as ulcers (diabetic, vascular and chronic), postoncologic resections (i.e., radical vulvectomy) or dermatologic disorders. The introduction in recent decades of acellular dermal matrices (ADMs) supporting the repair and restoration of skin functionality represented a significant step toward achieving clean wound repair before performing skin grafts. Hard-to-heal ulcers generally depend on local ischemia and nonadequate vascularization. In this context, one possible innovative approach could be the prevascularization of matrices with vessel-forming cells (inosculation). This paper presents a comparative analysis of the most widely used dermal templates, i.e., Integra

Indexed as

acellular dermal matrices (ADMs)angiogenesischronic woundsendothelial cellswound healing

Identifiers

PMID34680575
PMCPMC8533449
OpenAlexW3205814344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.