Evidence map›Paper›PMID 34680509›Full record

ArticleBiomedicines2021

Novel Biodegradable Composite of Calcium Phosphate Cement and the Collagen I Mimetic P-15 for Pedicle Screw Augmentation in Osteoporotic Bone.

Harald Krenzlin, Andrea Foelger, Volker Mailänder, Christopher Blase, Marc Brockmann, Christoph Düber, Florian Ringel, Naureen Keric

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Harald KrenzlinDepartment of Neurosurgery, University Medical Center Mainz, 55131 Mainz, Germany.
Andrea FoelgerDepartment of Neurosurgery, University Medical Center Mainz, 55131 Mainz, Germany.
Volker MailänderMax Planck Institute for Polymer Research, 55128 Mainz, Germany.
Christopher BlasePersonalized Biomedical Engineering Lab, Frankfurt University of Applied Sciences, 60318 Frankfurt am Main, Germany.
Marc BrockmannDepartment of Neuroradiology, University Medical Center Mainz, 55131 Mainz, Germany.
Christoph DüberDepartment of Radiology, University Medical Center Mainz, 55131 Mainz, Germany.
Florian RingelDepartment of Neurosurgery, University Medical Center Mainz, 55131 Mainz, Germany.
Naureen KericDepartment of Neurosurgery, University Medical Center Mainz, 55131 Mainz, Germany.
Johannes Gutenberg University Mainz · DEUniversity Medical Center of the Johannes Gutenberg University Mainz · DEFrankfurt University of Applied Sciences · DE

Funding

DFG ( BioMaTiCS)
6 · The paper itself

Abstract

Osteoporotic vertebral fractures often necessitate fusion surgery, with high rates of implant failure. We present a novel bioactive composite of calcium phosphate cement (CPC) and the collagen I mimetic P-15 for pedicle screw augmentation in osteoporotic bone. Methods involved expression analysis of osteogenesis-related genes during osteoblastic differentiation by RT-PCR and immunostaining of osteopontin and Ca

Indexed as

calcium phosphate cementcollagen I mimetic P-15osteoporosisosteoporotic vertebral fracturespolymethylmethacrylate

Identifiers

PMID34680509
PMCPMC8533375
OpenAlexW3204125093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.