Evidence map›Paper›PMID 34680501›Full record

ArticleBiomedicines2021

A DNA Damage Response Gene Panel for Different Histologic Types of Epithelial Ovarian Carcinomas and Their Outcomes.

Ying-Cheng Chiang, Po-Han Lin, Tzu-Pin Lu, Kuan-Ting Kuo, Yi-Jou Tai, Heng-Cheng Hsu, Chia-Ying Wu, Chia-Yi Lee, Hung Shen, Chi-An Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Ying-Cheng ChiangDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100226, Taiwan.ORCID 0000-0002-8958-5222
Po-Han LinDepartment of Medical Genetics, National Taiwan University Hospital, Taipei 100226, Taiwan.
Tzu-Pin LuInstitute of Epidemiology and Preventive Medicine, Department of Public Health, National Taiwan University, Taipei 100025, Taiwan.
Kuan-Ting KuoDepartment of Pathology, College of Medicine, National Taiwan University, Taipei 100225, Taiwan.
Yi-Jou TaiDepartment of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei 100226, Taiwan.ORCID 0000-0003-1442-0850
Heng-Cheng HsuGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100225, Taiwan.ORCID 0000-0002-6817-0693
Chia-Ying WuDepartment of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei 100226, Taiwan.
Chia-Yi LeeGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100225, Taiwan.ORCID 0000-0002-2689-4685
Hung ShenGraduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100225, Taiwan.
Chi-An ChenDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100226, Taiwan.
Wen-Fang ChengDepartment of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei 100226, Taiwan.
National Taiwan University · TW

Funding

National Taiwan University Hospital 105-N02, UN105-059, 108-S4230 and 109-S4570
6 · The paper itself

Abstract

DNA damage response (DDR) is important for maintaining genomic integrity of the cell. Aberrant DDR pathways lead to accumulation of DNA damage, genomic instability and malignant transformations. Gene mutations have been proven to be associated with epithelial ovarian cancer, and the majority of the literature has focused on

Indexed as

clear cell carcinomaDNA damage responseepithelial ovarian cancersomatic mutation

Identifiers

PMID34680501
PMCPMC8533221
OpenAlexW3205939010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.