Evidence map›Paper›PMID 34680491›Full record

ArticleBiomedicines2021

Synthesis, In Silico Study, and Anti-Cancer Activity of Thiosemicarbazone Derivatives.

Belay Zeleke Sibuh, Piyush Kumar Gupta, Pankaj Taneja, Sonia Khanna, Paratpar Sarkar, Sanya Pachisia, Abrar Ali Khan, Niraj Kumar Jha, Kamal Dua, Sachin Kumar Singh and 4 more

Abstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. L-proline HMolecular diversity · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Belay Zeleke SibuhDepartment of Biotechnology, School of Engineering and Technology (SET), Sharda University, Knowledge Park III, Greater Noida 201310, Uttar Pradesh, India.
Piyush Kumar GuptaDepartment of Life Sciences, School of Basic Sciences and Research (SBSR), Sharda University, Knowledge Park III, Greater Noida 201310, Uttar Pradesh, India.ORCID 0000-0002-3346-910X
Pankaj TanejaDepartment of Biotechnology, School of Engineering and Technology (SET), Sharda University, Knowledge Park III, Greater Noida 201310, Uttar Pradesh, India.
Sonia KhannaDepartment of Chemistry and Biochemistry, School of Basic Sciences and Research (SBSR), Sharda University, Knowledge Park III, Greater Noida 201310, Uttar Pradesh, India.
Paratpar SarkarDepartment of Chemistry and Biochemistry, School of Basic Sciences and Research (SBSR), Sharda University, Knowledge Park III, Greater Noida 201310, Uttar Pradesh, India.
Sanya PachisiaDepartment of Chemistry, University of Delhi, New Delhi 110007, Delhi, India.
Abrar Ali KhanDepartment of Biotechnology, Indian Institute of Technology, Chennai 600036, Tamilnadu, India.
Niraj Kumar JhaDepartment of Biotechnology, School of Engineering and Technology (SET), Sharda University, Knowledge Park III, Greater Noida 201310, Uttar Pradesh, India.ORCID 0000-0001-9486-4069
Kamal DuaDiscipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-7507-1159
Sachin Kumar SinghSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara 144001, Punjab, India.
Sadanand PandeyDepartment of Chemistry, College of Natural Science, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, Gyeongbuk, Korea.ORCID 0000-0003-2065-897X
Petr SlamaDepartment of Animal Morphology, Physiology and Genetics, Faculty of AgriSciences, Mendel University in Brno, 61300 Brno, Czech Republic.ORCID 0000-0003-0570-259X
Kavindra Kumar KesariDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, 00076 Espoo, Finland.ORCID 0000-0003-3622-9555
Shubhadeep RoychoudhuryDepartment of Life Science and Bioinformatics, Assam University, Silchar 788011, Assam, India.ORCID 0000-0003-4174-1852

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiosemicarbazones are known for their biological and pharmacological activities. In this study, we have synthesized and characterized 3-Methoxybenzaldehyde thiosemicarbazone (3-MBTSc) and 4-Nitrobenzaldehyde thiosemicarbazone (4-NBTSc) using IR,

Indexed as

3-Methoxybenzaldehyde thiosemicarbazone4-Nitrobenzaldehyde thiosemicarbazoneB16-F0 melanomacancerin silico ADMETMCF-7molecular docking

Identifiers

PMID34680491
PMCPMC8533299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.