Evidence map›Paper›PMID 34680321›Full record

ReviewCancers2021

PET with Different Radiopharmaceuticals in Neuroendocrine Neoplasms: An Umbrella Review of Published Meta-Analyses.

Giorgio Treglia, Ramin Sadeghi, Francesco Giovinazzo, Federica Galiandro, Salvatore Annunziata, Barbara Muoio, Alexander Stephan Kroiss

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Research process of PET tracers for neuroendocrine tumors diagnosis.American journal of nuclear medicine and molecular imaging · 2025
    Review
  6. Endocrinology application of molecular imaging: current role of PET/CT.Journal of endocrinological investigation · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. [Neuroendocrine tumors of the pancreas].Radiologie (Heidelberg, Germany) · 2023
    Review
  11. Review
  12. Review
  13. Relevance of Volumetric Parameters Applied to [Diagnostics (Basel, Switzerland) · 2023
    Article
  14. Article
  15. [Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
  16. Review
  17. Article
  18. Prevalence of Brain Incidental Lesions Detected byMedicina (Kaunas, Lithuania) · 2022
    Article
  19. Review
  20. New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms.Current treatment options in oncology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Giorgio TregliaClinic of Nuclear Medicine, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.ORCID 0000-0001-9808-780X
Ramin SadeghiNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad 9919991766, Iran.
Francesco GiovinazzoDipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-3392-9292
Federica GaliandroDipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-5041-4867
Salvatore AnnunziataUOC Medicina Nucleare, TracerGLab, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Barbara MuoioDepartment of Medicine and Oncology, Institute of Southern Switzerland, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland.
Alexander Stephan KroissDepartment of Nuclear Medicine, Medical University Innsbruck, 6020 Innsbruck, Austria.
Agostino Gemelli University Polyclinic · ITEnte Ospedaliero Cantonale · CHInnsbruck Medical University · ATMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral meta-analyses have reported quantitative data about the diagnostic performance, the prognostic value, the impact on management and the safety of positron emission tomography (PET) including related hybrid modalities (PET/CT or PET/MRI) using different radiopharmaceuticals in patients with neuroendocrine neoplasms. We performed an umbrella review of published meta-analyses to provide an evidence-based summary.

methodsA comprehensive literature search of meta-analyses listed in PubMed/MEDLINE and Cochrane Library databases was carried out (last search date: 30 June 2021).

resultsThirty-four published meta-analyses were selected and summarized. About the diagnostic performance:

conclusionsEvidence-based data support the use of PET with different radiopharmaceuticals in patients with neuroendocrine neoplasms with specific indications for each radiopharmaceutical.

Indexed as

diagnostic performanceimpactmeta-analysisneuroendocrinePETpositron emission tomographyprognosisumbrella review

Identifiers

PMID34680321
PMCPMC8533943
OpenAlexW3205746683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.