Evidence map›Paper›PMID 34680289›Full record

ArticleCancers2021

Predicting Tumor Budding Status in Cervical Cancer Using MRI Radiomics: Linking Imaging Biomarkers to Histologic Characteristics.

Gun Oh Chong, Shin-Hyung Park, Nora Jee-Young Park, Bong Kyung Bae, Yoon Hee Lee, Shin Young Jeong, Jae-Chul Kim, Ji Young Park, Yu Ando, Hyung Soo Han

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gun Oh ChongDepartment of Obstetrics and Gynecology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.ORCID 0000-0003-4887-4017
Shin-Hyung ParkDepartment of Radiation Oncology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.ORCID 0000-0003-0291-8985
Nora Jee-Young ParkClinical Omics Research Center, School of Medicine, Kyungpook National University, Daegu 41944, Korea.ORCID 0000-0002-1857-813X
Bong Kyung BaeDepartment of Radiation Oncology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Yoon Hee LeeDepartment of Obstetrics and Gynecology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Shin Young JeongDepartment of Nuclear Medicine, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Jae-Chul KimDepartment of Radiation Oncology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Ji Young ParkDepartment of Pathology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.ORCID 0000-0002-7571-1064
Yu AndoCardiovascular Research Institute, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Hyung Soo HanClinical Omics Research Center, School of Medicine, Kyungpook National University, Daegu 41944, Korea.ORCID 0000-0001-7200-0921

Funding

National Research Foundation of Korea 2019R1G1A1089358National Research Foundation of Korea 2020R1G1A1102848
6 · The paper itself

Abstract

backgroundOur previous study demonstrated that tumor budding (TB) status was associated with inferior overall survival in cervical cancer. The purpose of this study is to evaluate whether radiomic features can predict TB status in cervical cancer patients.

methodsSeventy-four patients with cervical cancer who underwent preoperative MRI and radical hysterectomy from 2011 to 2015 at our institution were enrolled. The patients were randomly allocated to the training dataset (

resultsTwenty radiomic features were selected; all were features from filtered-images and 85% were texture-related features. The area under the curve values and accuracy of the models by LR, RF, SVM and NN were 0.742 and 0.769, 0.782 and 0.731, 0.849 and 0.885, and 0.891 and 0.731, respectively, in the test dataset.

conclusionMRI-based radiomic features could predict TB status in patients with cervical cancer.

Indexed as

cervical cancermagnetic resonance imagingradiomicstumor budding

Identifiers

PMID34680289
PMCPMC8534175

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.