Evidence map›Paper›PMID 34680093›Full record

ArticleBiomolecules2021

Description of Joint Alterations Observed in a Family Carrying p.Asn453Ser

Quitterie Rochoux, Jana Sopkova-de Oliveira Santos, Christian Marcelli, Anne Rovelet-Lecrux, Virginie Chevallier, Jean-Jacques Dutheil, Sylvain Leclercq, Karim Boumédiene, Catherine Baugé, Juliette Aury-Landas

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Quitterie RochouxEA7451 BioConnecT, Normandie Université, UNICAEN, 14032 Caen, France.
Jana Sopkova-de Oliveira SantosEA4258 CERMN, Normandie Université, UNICAEN, 14032 Caen, France.ORCID 0000-0002-4829-8120
Christian MarcelliService de Rhumatologie, CHU de Caen, 14000 Caen, France.
Anne Rovelet-LecruxDepartment of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Normandie Université, UNIROUEN, Inserm U1245 and Rouen University Hospital, 76000 Rouen, France.ORCID 0000-0003-4454-3659
Virginie ChevallierDélégation de la Recherche Clinique et de l'Innovation, CHU de Caen, 14000 Caen, France.
Jean-Jacques DutheilDélégation de la Recherche Clinique et de l'Innovation, CHU de Caen, 14000 Caen, France.
Sylvain LeclercqEA7451 BioConnecT, Normandie Université, UNICAEN, 14032 Caen, France.
Karim BoumédieneEA7451 BioConnecT, Normandie Université, UNICAEN, 14032 Caen, France.
Catherine BaugéEA7451 BioConnecT, Normandie Université, UNICAEN, 14032 Caen, France.ORCID 0000-0001-5642-998X
Juliette Aury-LandasEA7451 BioConnecT, Normandie Université, UNICAEN, 14032 Caen, France.ORCID 0000-0002-7531-5088
Normandie Université · FRCentre Hospitalier Universitaire de Caen Normandie · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of genetics in the development of osteoarthritis is well established but the molecular bases are not fully understood. Here, we describe a family carrying a germline mutation in

Indexed as

Genetic Predisposition to DiseaseAdultCartilage Oligomeric Matrix ProteinFemaleGenetic VariationGerm-Line MutationHumansJointsMaleMiddle AgedMolecular Dynamics SimulationMutation, MissenseOsteoarthritisOsteochondrodysplasiasProtein ConformationStructure-Activity RelationshipCartilage Oligomeric Matrix ProteinTSP5 protein, humanarthritisCOMPdysplasiageneticsmutationosteoarthritis

Identifiers

PMID34680093
PMCPMC8533395
OpenAlexW3205109400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.