ReviewBiomolecules2021
Natural Products Are a Promising Source for Anthelmintic Drug Discovery.
Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 73 citations in OpenAlex.
- Chemical investigation and anti-trichinellosis activity of some ficus species leaves: in silico supported in vitro study.BMC complementary medicine and therapies · 2026Article
- The Role of Natural Anthelmintics in Small Ruminant Health: A Global Narrative Review.Animals : an open access journal from MDPI · 2026Review
- Larvicidal and antioxidant potential of Iranian Propolis againstVeterinary world · 2026Article
- Ethnobotanical anthelmintics of the Napu People in Indonesia during the schistosomiasis-endemic.Open veterinary journal · 2026Article
- Anti-onchocerca activity, toxicity and induced biochemical changes ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
- Article
- Harnessing Plant-Derived Terpenoids for Novel Approaches in Combating Bacterial and Parasite Infections in Veterinary and Agricultural Settings.Current microbiology · 2025Review
- The Anthelmintic Activity of Stonefish (Toxins · 2025Article
- Exploring Metabolic Disruption and Redox Modulation by Senna Leaf Extracts Induces Mortality in the Zoonotic ParasiteJournal of parasitology research · 2025Article
- Article
- Potency of anti-trematode in inhibiting cathepsin-2L and cathepsin-5L ofOpen veterinary journal · 2024Article
- Unlocking the combined action ofHeliyon · 2024Article
- Synergistic Interaction Effect of Artemisia cina n-hexane Extract and Tagetes lucida Ethyl Acetate Extract on Haemonchus Contortus.Acta parasitologica · 2024Article
- Antiparasitic activity of the steroid-rich extract ofVeterinary world · 2024Article
- Synthesis of Rhodamine-Conjugated Lupane Type Triterpenes of Enhanced Cytotoxicity.Molecules (Basel, Switzerland) · 2024Article
- Anthelmintic Effect of Cannabidiol againstTropical medicine and infectious disease · 2024Article
- Effect of pomegranate (Frontiers in veterinary science · 2024Article
- Identification of bio-active secondary metabolites from Actinobacteria as potential drug targets againstIn silico pharmacology · 2024Article
- Paraherquamides - A new hope and great expectations of anthelmintic agents: Computational studies.PloS one · 2024Article
- Botanicals against some important nematodal diseases: Ascariasis and hookworm infections.Saudi journal of biological sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parasitic nematodes infect almost all forms of life. In the human context, parasites are one of the major causative factors for physical and intellectual growth retardation in the developing world. In the agricultural setting, parasites have a great economic impact through a reduction in livestock performance or control cost. The main method of controlling these devastating conditions is the use of anthelmintic drugs. Unfortunately, there are only a few anthelmintic drug classes available in the market and significant resistance has developed in most of the parasitic species of livestock. Therefore, development of new anthelmintics with different modes of action is critical for sustainable parasitic control in the future. The drug development pipeline is broadly limited to two types of molecules, namely synthetic compounds and natural plant products. Compared to synthetic compounds, natural products are highly diverse, and many have historically proven valuable in folk medicine to treat various gastrointestinal ailments. This review focus on the use of traditional knowledge-based plant extracts in the development of new therapeutic leads, the approaches used as screening techniques, and common bottlenecks and opportunities in plant-based anthelmintic drug discovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.