Evidence map›Paper›PMID 34680046›Full record

ArticleBiomolecules2021

Feeling the Heat: The

Giovanni Versace, Marta Palombo, Anna Menon, Vincenzo Scarlato, Davide Roncarati

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. ClpB enhances thermotolerance inMicrobiology spectrum · 2025
    Article
  5. Article
  6. Insights into the Orchestration of Gene Transcription Regulators inInternational journal of molecular sciences · 2022
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Giovanni VersaceDepartment of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy.
Marta PalomboDepartment of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy.
Anna MenonDepartment of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy.
Vincenzo ScarlatoDepartment of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-4227-677X
Davide RoncaratiDepartment of Pharmacy and Biotechnology (FaBiT), University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-6923-6087
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heat-shock response, a universal protective mechanism consisting of a transcriptional reprogramming of the cellular transcriptome, results in the accumulation of proteins which counteract the deleterious effects of heat-stress on cellular polypeptides. To quickly respond to thermal stress and trigger the heat-shock response, bacteria rely on different mechanisms to detect temperature variations, which can involve nearly all classes of biological molecules. In

Indexed as

Campylobacter jejuniDNA-Binding ProteinsGene Expression Regulation, BacterialHeat-Shock ProteinsHeat-Shock ResponseOperonPromoter Regions, GeneticRepressor ProteinsDNA-Binding ProteinsHeat-Shock ProteinsRepressor ProteinsCampylobacter jejuniDNA-protein interactionGroE chaperoninheat-shock proteinsheat-shock responseHrcA repressorHspR repressorsignal perceptiontranscriptional regulation

Identifiers

PMID34680046
PMCPMC8533110
OpenAlexW3201894385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.