Evidence map›Paper›PMID 34679989›Full record

ArticleAnimals : an open access journal from MDPI2021

A Methodology to Quantify Resilience in Growing Pigs.

Houda Laghouaouta, Ramona N Pena, Roger Ros-Freixedes, Josep Reixach, Marta Díaz, Joan Estany, Ramon Armengol, Anna Bassols, Lorenzo Fraile

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Sequence variants associated with resilient responses in growing pigs.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025
    Article
  6. Selection for Resilience in Livestock Production Systems.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. A genome-wide screen for resilient responses in growing pigs.Genetics, selection, evolution : GSE · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Houda LaghouaoutaAgrotecnio-CERCA Center, Department of Animal Science, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0002-8578-120X
Ramona N PenaAgrotecnio-CERCA Center, Department of Animal Science, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0002-3558-7302
Roger Ros-FreixedesAgrotecnio-CERCA Center, Department of Animal Science, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0002-3745-6736
Josep ReixachSelección Batallé SA, 17421 Riudarenes, Spain.
Marta DíazSelección Batallé SA, 17421 Riudarenes, Spain.
Joan EstanyAgrotecnio-CERCA Center, Department of Animal Science, University of Lleida, 25198 Lleida, Spain.
Ramon ArmengolAgrotecnio-CERCA Center, Department of Animal Science, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0001-5293-193X
Anna BassolsDepartament de Bioquímica, Universitat Autónoma de Barcelona, 08193 Barcelona, Spain.ORCID 0000-0003-4213-2274
Lorenzo FraileAgrotecnio-CERCA Center, Department of Animal Science, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0002-8980-5862
Universitat de Lleida · ESUniversitat Autònoma de Barcelona · ES

Funding

Spanish National Research Council RTI2018-097700-B-I00
6 · The paper itself

Abstract

There is a growing concern about the genetic determinism of resilience and its possible implementation in breeding programs. The objective of our study was to elaborate novel resilience indicators in growing pigs based on the deviation from the expected growth curve and the increment of the acute-phase protein haptoglobin (HP) after applying a common vaccine. A total of 445 pigs were vaccinated with an attenuated Aujeszky vaccine at 12 weeks of age. Deviation from the expected body weight (ΔBW) given the growth curve of unvaccinated pigs at 28 days post-vaccination (DPV) and the increment of HP at 4 DPV (ΔHP) were suggested as resilience indicators. Challenged pigs that maintained their productivity and had a minor activation of HP were deemed resilient, whereas pigs that had low ∆BW values and a high activation of HP were deemed susceptible. Pigs were also classified based on ∆BW and ∆HP relative to the expected BW at 28 DPV and to the basal level of HP, respectively. The concordance was high between both methods, indicating that ΔBW and ΔHP are not sensitive to the animal's expected BW nor the basal level of HP. The heritability estimates were moderate for ∆BW (0.33) and low-to-moderate for ∆HP (0.16). Our study suggests ΔBW and ΔHP as novel resilience indicators in pigs. The suggested indicators capture different aspects of resilience, are easy to measure, and are genetically controlled. Thus, they may be improved through selective breeding. Further analyses are needed to validate our findings.

Indexed as

body weighthaptoglobinpigsresilience indicatorsvaccine challenge

Identifiers

PMID34679989
PMCPMC8532637
OpenAlexW3206968060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.