Evidence map›Paper›PMID 34679955›Full record

ArticleAnimals : an open access journal from MDPI2021

Morphology of the Spleen in

Yang He, Erlong Wang, Kaiyu Wang, Jun Wang, Wei Fan, Defang Chen, Qian Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Pathogenic Characterization and Host Immune Response toAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yang HeKey Laboratory of Animal Disease and Human Health of Sichuan Province, Department of Basic Veterinary, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang 611130, China.
Erlong WangCollege of Animal Science and Technology, Northwest A&F University, Xianyang 712100, China.
Kaiyu WangKey Laboratory of Animal Disease and Human Health of Sichuan Province, Department of Basic Veterinary, College of Veterinary Medicine, Sichuan Agricultural University, Wenjiang 611130, China.
Jun WangKey Laboratory of Sichuan Province for Fishes Conservation and Utilization in the Upper Reaches of the Yangtze River, Neijiang Normal University, Neijiang 641000, China.
Wei FanNeijiang City Academy of Agricultural Sciences, Neijiang 641000, China.
Defang ChenDepartment of Aquaculture, College of Animal Science & Technology, Sichuan Agricultural University, Wenjiang 611130, China.
Qian YangLaboratory Animal Center, Southwest Medical University, Longmatan District Xianglin Road No.1, Luzhou 646000, China.
Sichuan Agricultural University · CNNeijiang Normal University · CNNorthwest A&F University · CNSouthwest Medical University · CN

Funding

The Opening Fund of Key Laboratory of Sichuan Province for Fishes Conservation and Utilization in the Upper Reaches of the Yangtze River (No. NJTCCJSYSYS09)The program for Changjiang Scholars and Innovative Research Teams in the University (No. IRT0848)
6 · The paper itself

Abstract

The spleen is a separate organ of the teleost, playing an essential role in immune reactions. The morphology of the spleen is different from the fish species. Little knowledge about the spleen structure and the blood splenic barrier (BSB) in Nile tilapia has been reported. To address this issue, we studied the histology of the spleen and the BSB in healthy Nile tilapia. The morphology of the spleen was observed, then H&E staining, modified Jame's staining, and ultrastructural techniques were performed to portion the spleen into three subregions and analyze the location of components and fibers. Thereafter, vital staining of Nile tilapia with Trypan blue was conducted to elucidate the composition and function of BSB. Histologically, the spleen could be divided into three subregions (inner, middle, and outer). The venules, clumps of lymphocytes, and vessels were separately characterized features of the outer, middle, and inner layers. Post injection, Trypan blue was intercepted in the endotheliocytes of ellipsoids in the middle layer (

Indexed as

blood-spleen barrierNile tilapiaspleensubregion

Identifiers

PMID34679955
PMCPMC8532917
OpenAlexW3206298898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.