Evidence map›Paper›PMID 34679878›Full record

ArticleAnimals : an open access journal from MDPI2021

Changes in Serum Thiol-Disulphide Homeostasis in Sheep with Gastrointestinal Nematodes.

Elizabeth Moreira Dos Santos Schmidt, Daniele Floriano Fachiolli, Raphaela Moreira de Oliveira, Fabiana Alves Almeida, Cristiano Magalhães Pariz, Paulo Roberto de Lima Meirelles, Ciniro Costa, Asta Tvarijonaviciute, Ozcan Erel, Salim Neselioglu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Elizabeth Moreira Dos Santos SchmidtDepartment of Veterinary Clinical Sciences, School of Veterinary Medicine and Animal Science, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0001-8297-6979
Daniele Floriano FachiolliDepartment of Animal Nutrition and Breeding, School of Veterinary Medicine and Animal Science, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-4116-9289
Raphaela Moreira de OliveiraDepartment of Veterinary Clinical Sciences, School of Veterinary Medicine and Animal Science, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.
Fabiana Alves AlmeidaDepartment of Parasitology, Biosciences Institute, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-4479-6480
Cristiano Magalhães ParizDepartment of Animal Nutrition and Breeding, School of Veterinary Medicine and Animal Science, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.
Paulo Roberto de Lima MeirellesDepartment of Animal Nutrition and Breeding, School of Veterinary Medicine and Animal Science, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0001-9168-5081
Ciniro CostaDepartment of Animal Nutrition and Breeding, School of Veterinary Medicine and Animal Science, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.
Asta TvarijonaviciuteInterdisciplinary Laboratory of Clinical Analysis of the University of Murcia (Interlab-UMU), Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, Espinardo, 30100 Murcia, Spain.ORCID 0000-0002-5323-5001
Ozcan ErelDepartment of Biochemistry, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara City Hospital, Ankara 06800, Turkey.
Salim NeseliogluDepartment of Biochemistry, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara City Hospital, Ankara 06800, Turkey.
Jose Joaquin CeronInterdisciplinary Laboratory of Clinical Analysis of the University of Murcia (Interlab-UMU), Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, Espinardo, 30100 Murcia, Spain.
Camila Peres RubioDepartment of Veterinary Clinical Sciences, School of Veterinary Medicine and Animal Science, Campus of Botucatu, São Paulo State University (FMVZ-UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-9293-4147
Universidade Estadual Paulista (Unesp) · BRAnkara Yıldırım Beyazıt University · TRUniversidad de Murcia · ESCentro Universitário do Distrito Federal · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/05055
6 · The paper itself

Abstract

This work aimed to evaluate the thiol-disulphide homeostasis in serum of lambs naturally infected by gastrointestinal nematodes presenting different levels of parasite load indirectly indicated by faecal worm egg counts (EPG). Furthermore, the possible changes in the thiol-disulphide dynamic after different procedures to reduce the parasitic charge, such as the integrated crop-livestock system or anthelmintic treatment, were assessed. The results were compared with a panel of various oxidative stress and inflammatory biomarkers. The lambs were divided into three groups: animals highly infected (EPG higher than 5000) and packed cell volume (PCV) lower than 24% (G1); animals highly infected (EPG higher than 5000) and normal PCV (>24%) (G2); and animals presenting EPG lower than 5000 and normal PCV (>24%) (G3). The highly infected lambs (G1 and G2) showed lower total thiol (TT) and native thiol (SH) (

Indexed as

antioxidantclosantelHaemonchusintegrated crop-livestockoxidative stressruminants

Identifiers

PMID34679878
PMCPMC8532846
OpenAlexW3202785590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.