Evidence map›Paper›PMID 34679716›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Metabolic and Transcriptional Adaptations Improve Physical Performance of Zebrafish.

Franziska J Heinkele, Bowen Lou, Vanessa Erben, Katrin Bennewitz, Gernot Poschet, Carsten Sticht, Jens Kroll

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Novel nerve regeneration assessment method using adult zebrafish with crush spinal cord injury.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2025
    Article
  4. Metabolic effects of physical exercise on zebrafish (Danio rerio) fed a high-fat diet.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Franziska J HeinkeleDepartment of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, D-68167 Mannheim, Germany.
Bowen LouDepartment of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, D-68167 Mannheim, Germany.
Vanessa ErbenDepartment of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, D-68167 Mannheim, Germany.
Katrin BennewitzDepartment of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, D-68167 Mannheim, Germany.
Gernot PoschetMetabolomics Core Technology Platform, Centre for Organismal Studies, Heidelberg University, D-69120 Heidelberg, Germany.ORCID 0000-0002-5344-0865
Carsten StichtNGS Core Facility, Medical Faculty Mannheim, Heidelberg University, D-68167 Mannheim, Germany.
Jens KrollDepartment of Vascular Biology and Tumor Angiogenesis, European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, D-68167 Mannheim, Germany.
Heidelberg University · DE

Funding

Deutsche Forschungsgemeinschaft CRC1118 and IRTG 389 1874/2 DIAMICOMDr. Rolf M. Schwiete Stiftung 220-017
6 · The paper itself

Abstract

Obesity is a worldwide public health problem with increasing prevalence and affects 80% of diabetes mellitus type 2 cases. Zebrafish (

Indexed as

blood glucosedanio reriodiabetesmetabolomicsphysical activitytranscriptional profile

Identifiers

PMID34679716
PMCPMC8533608
OpenAlexW3204970251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.