Evidence map›Paper›PMID 34679606›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Machine Learning-Based Three-Month Outcome Prediction in Acute Ischemic Stroke: A Single Cerebrovascular-Specialty Hospital Study in South Korea.

Dougho Park, Eunhwan Jeong, Haejong Kim, Hae Wook Pyun, Haemin Kim, Yeon-Ju Choi, Youngsoo Kim, Suntak Jin, Daeyoung Hong, Dong Woo Lee and 2 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dougho ParkDepartment of Rehabilitation Medicine, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.ORCID 0000-0002-1288-470X
Eunhwan JeongDepartment of Neurology, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Haejong KimDepartment of Neurology, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Hae Wook PyunDepartment of Radiology, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Haemin KimDepartment of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Yeon-Ju ChoiDepartment of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Youngsoo KimDepartment of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Suntak JinDepartment of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Daeyoung HongDepartment of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Dong Woo LeeDepartment of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Su Yun LeeDepartment of Neurology, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.
Mun-Chul KimDepartment of Neurosurgery, Pohang Stroke and Spine Hospital, Pohang 37659, Korea.ORCID 0000-0002-2232-065X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional outcomes after acute ischemic stroke are of great concern to patients and their families, as well as physicians and surgeons who make the clinical decisions. We developed machine learning (ML)-based functional outcome prediction models in acute ischemic stroke.

methodsThis retrospective study used a prospective cohort database. A total of 1066 patients with acute ischemic stroke between January 2019 and March 2021 were included. Variables such as demographic factors, stroke-related factors, laboratory findings, and comorbidities were utilized at the time of admission. Five ML algorithms were applied to predict a favorable functional outcome (modified Rankin Scale 0 or 1) at 3 months after stroke onset.

resultsRegularized logistic regression showed the best performance with an area under the receiver operating characteristic curve (AUC) of 0.86. Support vector machines represented the second-highest AUC of 0.85 with the highest F1-score of 0.86, and finally, all ML models applied achieved an AUC > 0.8. The National Institute of Health Stroke Scale at admission and age were consistently the top two important variables for generalized logistic regression, random forest, and extreme gradient boosting models.

conclusionsML-based functional outcome prediction models for acute ischemic stroke were validated and proven to be readily applicable and useful.

Indexed as

algorithmfunctional outcomeischemic strokemachine learningprediction

Identifiers

PMID34679606
PMCPMC8534707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.