ReviewDiagnostics (Basel, Switzerland)2021
The Value of a Complete Blood Count (CBC) for Sepsis Diagnosis and Prognosis.
Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06991686 (Prognostic Value of Procalcitonin Vs Platelet/Total Leukocytic Count Ratio in 28 Days Outcome in Severe Septic Patients), which is not on this map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prognostic Value of Procalcitonin Vs Platelet/Total Leukocytic Count Ratio in 28 Days Outcome in Severe Septic Patients
Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.
- Prognostic Value of Platelet to Lymphocyte Ratio in Sepsis: A Systematic Review and Meta-analysis.BioMed research international · 2022Pooled it
- Risk factors associated with treatment failure in peritoneal dialysis-associated peritonitis.Experimental and therapeutic medicine · 2026Article
- Hexosylceramide Species in the Blood Decline in Both COVID-19 and Non-COVID-19 Sepsis.Biomedicines · 2026Article
- Diagnostic value of the pan-immune inflammation value in methanol-induced optic neuropathy.Irish journal of medical science · 2026Article
- Comorbidities, Routine Biomarkers and Early Septic Shock Occurrence in Patients with Sepsis: A Retrospective Longitudinal Study.Diagnostics (Basel, Switzerland) · 2026Article
- Monocyte Distribution Width and Composite Biomarker Assessment for Prognostic Stratification of Sepsis in the Intensive Care Unit.Biomedicines · 2026Article
- Personalized Interpretation of CBC and the Role of CRP in Early Detection and Monitoring of Blood Infection or Sepsis: A Diagnostic Perspective.Health science reports · 2026Article
- Development of a machine learning-based sepsis prediction model for real-world clinical settings in South Korea: a single-center retrospective study.Journal of Korean biological nursing science · 2026Article
- Metabolic adaptations rewire CD4Nature immunology · 2026Article
- Immature Granulocyte Trajectories Following Hemadsorption as Indicators of Immune Dysregulation and Mortality.Journal of clinical medicine · 2026Article
- Assessing the Efficacy of Antibiotic Therapy: A Retrospective Study Comparing 875 mg vs. 500 mg of Amoxicillin/Clavulanic Acid for the Management of Acute Apical Abscesses.Dentistry journal · 2026Article
- Thrombomodulin protects against acute vascular and multiorgan injury in sickle cell disease.JCI insight · 2026Article
- Coagulation abnormalities in pediatric anemia clinical and laboratory correlates for risk stratification and risk assessment.Annals of medicine and surgery (2012) · 2026Review
- Development and validation of a diagnostic model for late-onset neonatal sepsis using the haematological profile: a retrospective cohort study.Intensive care medicine. Paediatric and neonatal · 2026Article
- The interplay between type 2 diabetes mellitus and sepsis: a scoping review.International journal of medical sciences · 2026Article
- Comparative evaluation of the aggregate index of systemic inflammation (AISI) and its modified version for early detection of central line-associated bloodstream infection: a pilot study using machine learning techniques.GMS hygiene and infection control · 2026Article
- Complete blood count (CBC)-derived indices at admission and short-term outcomes in ICU patients: a retrospective study.Annals of medicine · 2025Article
- Standard complete blood count to predict long-term outcomes in febrile infection-related epilepsy syndrome (FIRES): A multicenter study.Epilepsia · 2025Article
- Explainable AI unravels sepsis heterogeneity via coagulation-inflammation profiles for prognosis and stratification.Nature communications · 2025Observational
- Diagnostic Utility of Monocyte Distribution Width for Early Sepsis Detection in Cancer-Enriched Emergency Cohort.Journal of clinical medicine · 2025Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sepsis represents an important global health burden due to its high mortality and morbidity. The rapid detection of sepsis is crucial in order to prevent adverse outcomes and reduce mortality. However, the diagnosis of sepsis is still challenging and many efforts have been made to identify reliable biomarkers. Unfortunately, many investigated biomarkers have several limitations that do not support their introduction in clinical practice, such as moderate diagnostic and prognostic accuracy, long turn-around time, and high-costs. Complete blood count represents instead a precious test that provides a wealth of information on individual health status. It can guide clinicians to early-identify patients at high risk of developing sepsis and to predict adverse outcomes. It has several advantages, being cheap, easy-to-perform, and available in all wards, from the emergency department to the intensive care unit. Noteworthy, it represents a first-level test and an alteration of its parameters must always be considered within the clinical context, and the eventual suspect of sepsis must be confirmed by more specific investigations. In this review, we describe the usefulness of basic and new complete blood count parameters as diagnostic and prognostic biomarkers of sepsis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.