Evidence map›Paper›PMID 34679577›Full record

ArticleDiagnostics (Basel, Switzerland)2021

The ERG1A K

Sandra Zampieri, Marco Sandri, Joseph L Cheatwood, Rajesh P Balaraman, Luke B Anderson, Brittan A Cobb, Chase D Latour, Gregory H Hockerman, Helmut Kern, Roberta Sartori and 6 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. ERG1A KScientific reports · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Sandra ZampieriDepartment of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.ORCID 0000-0001-6970-0011
Marco SandriDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.
Joseph L CheatwoodAnatomy Department, Southern Illinois University School of Medicine, Carbondale, IL 62902, USA.ORCID 0000-0002-4051-0131
Rajesh P BalaramanDepartment of Chemistry and Biochemistry, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Luke B AndersonAnatomy Department, Southern Illinois University School of Medicine, Carbondale, IL 62902, USA.
Brittan A CobbAnatomy Department, Southern Illinois University School of Medicine, Carbondale, IL 62902, USA.
Chase D LatourDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Gregory H HockermanMedicinal Chemistry and Molecular Pharmacology Department, Purdue University School of Pharmacy, West Lafayette, IN 47906, USA.
Helmut KernPhysiko-und Rheumatherapie GmbH, 3100 St. Poelten, Austria.ORCID 0000-0001-9661-8814
Roberta SartoriDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-2763-9838
Barbara RavaraDepartment of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.
Stefano MeriglianoDepartment of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.
Gianfranco Da DaltDepartment of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.
Judith K DavieBiochemistry Department, Southern Illinois University School of Medicine, Carbondale, IL 62902, USA.
Punit KohliDepartment of Chemistry and Biochemistry, Southern Illinois University School of Medicine, Carbondale, IL 62901, USA.
Amber L PondAnatomy Department, Southern Illinois University School of Medicine, Carbondale, IL 62902, USA.
Southern Illinois University School of Medicine · USUniversity of Padua · ITPurdue University West Lafayette · USUniversity of North Carolina at Chapel Hill · US

Funding

A&C M-C Foundation for Translational Research Support to UCAustrian Federal Ministry of Science and Research Ludwig Boltzman to HKItalian Society for Cancer Research AIRC grant number 17388 to M SandriNational Science Foundation CHE 0748676 to PKNIH HHS GM 106364 to PKSouthern Illinois University Statrt Up to ALP
6 · The paper itself

Abstract

backgroundThe potassium channel encoded by the METHODS AND

resultsHere, using immunohistochemistry, we detect ERG1A immunofluorescence in human

conclusionsThe data demonstrate that ERG1A is detected more abundantly in the atrophied skeletal muscle of cancer patients, suggesting it may be related to muscle loss in humans as it has been shown to be in mice experiencing muscle atrophy as a result of malignant tumors.

Indexed as

cachexiadystrophinerg1apotassium channelrhabdomyosarcomasarcolemma membrane

Identifiers

PMID34679577
PMCPMC8534910
OpenAlexW3206205894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.