Evidence map›Paper›PMID 34679576›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Ocular Surface Temperature: Characterization in a Large Cohort of Healthy Human Eyes and Correlations to Systemic Cardiovascular Risk Factors.

Gal Yaakov Cohen, Gil Ben-David, Reut Singer, Sahar Benyosef, Rachel Shemesh, Ari Leshno, Yaniv Barkana, Alon Skaat

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Infrared thermography in clinical practice: a literature review.European journal of medical research · 2025
    Review
  7. Article
  8. Article
  9. Corneal Vascularization Associated With a Novel PDGFRB Variant.Investigative ophthalmology & visual science · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Gal Yaakov CohenThe Sam Rothberg Glaucoma Research Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262000, Israel.
Gil Ben-DavidThe Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0000-0001-9993-1005
Reut SingerThe Sam Rothberg Glaucoma Research Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262000, Israel.ORCID 0000-0002-8475-1017
Sahar BenyosefThe Sam Rothberg Glaucoma Research Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262000, Israel.
Rachel ShemeshThe Sam Rothberg Glaucoma Research Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262000, Israel.
Ari LeshnoThe Sam Rothberg Glaucoma Research Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262000, Israel.
Yaniv BarkanaThe Sam Rothberg Glaucoma Research Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262000, Israel.
Alon SkaatThe Sam Rothberg Glaucoma Research Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Ramat Gan 5262000, Israel.
Tel Aviv University · ILSheba Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo characterize ocular surface temperature (OST) in healthy eyes and its association with systemic risk factors of cardiovascular and ischemic heart disease.

methodsThis prospective cross-sectional study included consenting subjects who were examined at the Institute for Medical Screening in Sheba Medical Center. A Therm-App™ thermal imaging camera (Opgal LTD, Israel) was used for OST acquisition, and the mean OST of the medial canthal, lateral canthal, and central cornea regions were measured. Room and body temperatures were also recorded. Past medical and ocular history as well as data from various clinical examinations performed at the same visit were obtained.

resultsThermographic images were obtained from 186 subjects, 150 of which were included in the final analysis. OST was significantly higher in the medial canthal, central cornea, and lateral canthal regions in people with a history of ischemic heart disease (

conclusionsOST correlated positively with the presence of ischemic heart disease. This correlation, its pathophysiological base, and its clinical application warrants further investigation.

Indexed as

infrared thermographyischemic heart diseaseocular surface temperature

Identifiers

PMID34679576
PMCPMC8534589
OpenAlexW3207452912

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.