Development and Clinical Validation of the LymphMonitor Technology to Quantitatively Assess Lymphatic Function.

Anna Polomska, Epameinondas Gousopoulos, Daniel Fehr, Andreas Bachmann, Mathias Bonmarin, Michael Detmar, Nicole Lindenblatt

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In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anna PolomskaSwiss Federal Institute of Technology (ETH Zürich), Institute of Pharmaceutical Sciences, Vladimir-Prelog Weg 3, 8093 Zurich, Switzerland.

Epameinondas GousopoulosDepartment of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

Daniel FehrZurich University of Applied Sciences (ZHAW), Institute of Computational Physics, Technikumstrasse 9, 8401 Winterthur, Switzerland.ORCID 0000-0002-4863-8658

Andreas BachmannZurich University of Applied Sciences (ZHAW), Institute of Computational Physics, Technikumstrasse 9, 8401 Winterthur, Switzerland.

Mathias BonmarinZurich University of Applied Sciences (ZHAW), Institute of Computational Physics, Technikumstrasse 9, 8401 Winterthur, Switzerland.ORCID 0000-0003-0227-9247

Michael DetmarSwiss Federal Institute of Technology (ETH Zürich), Institute of Pharmaceutical Sciences, Vladimir-Prelog Weg 3, 8093 Zurich, Switzerland.ORCID 0000-0002-5351-5054

Nicole LindenblattDepartment of Plastic and Hand Surgery, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.

Funding

European Research Council advanced grant LYVICAMInnosuisse - Schweizerische Agentur für Innovationsförderung 29462.1 IP-LSSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_166490Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 310030_185392SKINTEGRITY flagship project of the University Medicine Zurich initiative 2/71018/16

6 · The paper itself

Abstract

Current diagnostic methods for evaluating the functionality of the lymphatic vascular system usually do not provide quantitative data and suffer from many limitations including high costs, complexity, and the need to perform them in hospital settings. In this work, we present a quantitative, simple outpatient technology named LymphMonitor to quantitatively assess lymphatic function. This method is based on the painless injection of the lymphatic-specific near-infrared fluorescent tracer indocyanine green complexed with human serum albumin, using MicronJet600

Indexed as

indocyanine greenlymphatic function monitoringlymphatic systemlymphedemalymphographymobile health

Identifiers

PMID34679571

DOI10.3390/diagnostics11101873

PMCPMC8534490

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