Evidence map›Paper›PMID 34679560›Full record

ArticleDiagnostics (Basel, Switzerland)2021

The Association between Mechanical Power and Mortality in Patients with Pneumonia Using Pressure-Targeted Ventilation.

Huang-Pin Wu, Chien-Ming Chu, Li-Pang Chuang, Shih-Wei Lin, Shaw-Woei Leu, Ko-Wei Chang, Li-Chung Chiu, Pi-Hua Liu, Kuo-Chin Kao

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. The role of mechanical power in lung ventilation for the prevention of ventilator-induced lung injury: a narrative review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. The Impact of Mechanical Energy Assessment on Mechanical Ventilation: A Comprehensive Review and Practical Application.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Huang-Pin WuDivision of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital, Keelung 20401, Taiwan.ORCID 0000-0002-8906-4566
Chien-Ming ChuDivision of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital, Keelung 20401, Taiwan.ORCID 0000-0002-0435-4645
Li-Pang ChuangCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0001-5466-8995
Shih-Wei LinCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-7915-0014
Shaw-Woei LeuCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Ko-Wei ChangCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0001-7058-6244
Li-Chung ChiuCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0003-1660-7715
Pi-Hua LiuClinical Informatics and Medical Statistics Research Center, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-7165-6248
Kuo-Chin KaoCollege of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-8777-1638
Chang Gung University · TW

Funding

Chang Gung Memorial Hospital CORPG3G0151
6 · The paper itself

Abstract

Recent studies have reported that mechanical power (MP) is associated with increased mortality in patients with acute respiratory distress syndrome (ARDS). We aimed to investigate the association between 28-day mortality and MP in patients with severe pneumonia. In total, the data of 313 patients with severe pneumonia were used for analysis. Serial MP was calculated daily for either 21 days or until ventilator support was no longer required. Compared with the non-ARDS group, the ARDS group (106 patients) demonstrated lower age, a higher Acute Physiology and Chronic Health Evaluation II score, lower history of diabetes mellitus, elevated incidences of shock and jaundice, higher MP and driving pressure on Day 1, and more deaths within 28 days. Regression analysis revealed that MP was an independent factor associated with 28-day mortality (odds ratio, 1.048; 95% confidence interval, 1.020-1.077). MP was persistently high in non-survivors and low in survivors among the ARDS group, the non-ARDS group, and all patients. These findings indicate that MP is associated with the 28-day mortality in ventilated patients with severe pneumonia, both in the ARDS and non-ARDS groups. MP had a better predicted value for the 28-day mortality than the driving pressure.

Indexed as

acute respiratory distress syndromedriving pressuremechanical powernon-acute respiratory distress syndromepneumonia

Identifiers

PMID34679560
PMCPMC8534721
OpenAlexW3206193816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.